Neuropharmacology

Birgit Hutter-Paier and Robert Wronski of QPS AustriaPublish On Orally Administered Neuroprotective Peptides to Prevent Brain Aging in Rats

Birgit Hutter-Paier and Robert Wronski of QPS Austria, with others, have published an article in the Journal of Medicine and Life on the effects of long-term intakeof neuroprotective peptides (N-PEP-12) on age-dependent memory loss in rats.

A novel dietary supplement produced from purified nerve cell proteins, N-PEP-12 has been shown to stimulate neurite outgrowth and have beneficial effects on neuronal survival with protection against metabolic stress in cell cultures. This activity is similar to that of naturally occurring peptide growth factors.

The rats’ improved performance in the Morris Water Maze and increased synaptic density as measured in the hippocampal formation and the entorhinal cortex suggest that the oral intake of N-PEP-12 may help maintain memory and learning performance during the aging process.

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