Evaluate therapeutic activity in acute intestinal inflammation with QPS’s dextran sulphate sodium (DSS)-induced colitis model. Established by administering DSS in drinking water, this widely used murine model supports preclinical evaluation of test articles for the treatment of ulcerative colitis (UC).

Incorporating this model into your pharmacology program can help characterize treatment effects, compare candidate compounds, and inform dose selection for subsequent studies.

Keep your mRNA program moving with strategies to address stability, delivery, and bioanalytical challenges. QPS combines bioanalytical expertise with responsive support to help you generate the data needed for your next development decision.

Read our Bioanalysis of mRNA white paper to explore therapeutic applications, delivery strategies, and analytical approaches, including RT-qPCR, immunoassays, and hybridization HPLC, and their roles in evaluating mRNA therapies.