Welcome to the Monthly QPS Preclinical Newsletter

Explore QPS pharmacology NASH models, discover more about QWBA studies, and stay updated with the latest research, breakthroughs, and insights on the QPS blog.

Greetings!

Explore the NEW QPS MASH Pharmacology Models

Metabolic Dysfunction-Associated Steatohepatitis (MASH), formerly Nonalcoholic Steatohepatitis (NASH), is a severe form of Nonalcoholic Fatty Liver Disease (NAFLD). There is a significant unmet need for new therapies to treat this debilitating disease. QPS has developed mouse models to support new drug development in this area.

QPS Model #1: Western Diet and Sugar Water-induced MASH Model

Male C57BL/6J mice will be fed a Western diet and sugar water for 28 weeks. The treatment of vehicle, test article or reference drugs will occur from Week 16 to Week 28.

Parameters to be evaluated: Body Weight, Serum Chemistry, Liver Weight, Liver histopathology (NAFLD activity score, liver fibrosis).

Contact QPS Today to Start Your Next MASH Study

Download the White Paper

Choosing the Right Imaging Method to Produce Tissue Distribution Data

Quantitative Whole-Body Autoradiography (QWBA)

The DMPK experts at QPS offer advanced quantitative whole body autoradiography (QWBA) studies to support drug development.

QWBA studies are particularly valuable to determine the visual location and tissue distribution of radiolabeled compounds in preclinical species. QWBA can be performed separately or combined with radiolabeled mass balance (MB) and plasma pharmacokinetic (PK) studies to provide high-resolution, quantitative data that can be used to characterize drug absorption, distribution, metabolism, and excretion (ADME) properties of drug candidates.

Contact QPS to secure a spot for your next QWBA study

Discover the Future of Science on the QPS Blog

Pharma Strikes Back at Compounding Pharmacies

Skim the pharma news outlet of your choice, and it’s clear that compounding pharmacies have been making headlines. These pharmacies typically provide one of three things: prescriptions for off-label...

Pharma Representatives Speak Out

Will you be at any of the following conferences?

QPS would love to meet with you.

WRIB - Booth# 47

New Orleans, LA

April 7-11, 2025

AAPS NBC - Booth# 212

New Orleans, LA

May 4-7, 2025

TIDES (Peptides and Oligonucleotides)

San Diego, CA

May 19-22, 2025

Schedule a Meeting with QPS

Visit our website www.qps.com

or contact us at info@qps.com

for an appointment.

www.qps.com | info@qps.com | +1 512 350 2827

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