Combined GPR40 and GPR119 full agonism with K-757 and K-833 results in robust glucose lowering and modest weight loss in overweight/obese subjects with T2DM QPS Combined GPR40 and GPR119 full agonism with K-757 and K-833 results in robust glucose lowering and modest weight loss in overweight/obese subjects with T2DM Read More ยป
Non-clinical and first-in-human characterization of ECC5004/AZD5004, a novel once-daily, oral small-molecule GLP-1 receptor agonist QPS Non-clinical and first-in-human characterization of ECC5004/AZD5004, a novel once-daily, oral small-molecule GLP-1 receptor agonist Read More ยป
Once-daily oral small-molecule glucagon-like peptide-1 receptor agonist lotiglipron (PF-07081532) for type 2 diabetes and obesity: Two randomized, placebo-controlled, multiple-ascending-dose Phase 1 studies QPS Once-daily oral small-molecule glucagon-like peptide-1 receptor agonist lotiglipron (PF-07081532) for type 2 diabetes and obesity: Two randomized, placebo-controlled, multiple-ascending-dose Phase 1 studies Read More ยป
LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial QPS LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial Read More ยป
Relative bioavailability and food effect of the galectinโ3 inhibitor selvigaltin (GB1211) administered as a tablet in healthy participants (GALBAโ1) QPS Relative bioavailability and food effect of the galectinโ3 inhibitor selvigaltin (GB1211) administered as a tablet in healthy participants (GALBAโ1) Read More ยป
A Phase 1 FirstโinโHuman SingleโAscendingโDose Trial With ESB1609, a Selective Agonist to the Sphingosineโ1โPhosphate Receptor 5 QPS A Phase 1 FirstโinโHuman SingleโAscendingโDose Trial With ESB1609, a Selective Agonist to the Sphingosineโ1โPhosphate Receptor 5 Read More ยป
Safety, Tolerability, Pharmacokinetics and Initial Pharmacodynamics of a Subcommissural Organ-Spondin-Derived Peptide: A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose First-in-Human Study QPS Safety, Tolerability, Pharmacokinetics and Initial Pharmacodynamics of a Subcommissural Organ-Spondin-Derived Peptide: A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose First-in-Human Study Read More ยป
Comparison of the Pharmacokinetic Profiles of Trientine Tetrahydrochloride and Trientine Dihydrochloride in Healthy Subjects QPS Comparison of the Pharmacokinetic Profiles of Trientine Tetrahydrochloride and Trientine Dihydrochloride in Healthy Subjects Read More ยป
Population Pharmacokinetic/Pharmacodynamic Modeling of Glenzocimab (ACT017) a Glycoprotein VI Inhibitor of CollagenโInduced Platelet Aggregation QPS Population Pharmacokinetic/Pharmacodynamic Modeling of Glenzocimab (ACT017) a Glycoprotein VI Inhibitor of CollagenโInduced Platelet Aggregation Read More ยป
Effect of RifampinโMediated OATP1B1 and OATP1B3 Transporter Inhibition on the Pharmacokinetics of the P2Y12 Receptor Antagonist Selatogrel QPS Effect of RifampinโMediated OATP1B1 and OATP1B3 Transporter Inhibition on the Pharmacokinetics of the P2Y12 Receptor Antagonist Selatogrel Read More ยป
Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT017, an Antiplatelet GPVI (Glycoprotein VI) Fab: First-in-Human Healthy Volunteer Trial QPS Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT017, an Antiplatelet GPVI (Glycoprotein VI) Fab: First-in-Human Healthy Volunteer Trial Read More ยป
Influence of Rifampin-Mediated Organic Anion-Transporting Polypeptide 1B1/1B3 Inhibition on the Pharmacokinetics of Clazosentan QPS Influence of Rifampin-Mediated Organic Anion-Transporting Polypeptide 1B1/1B3 Inhibition on the Pharmacokinetics of Clazosentan Read More ยป
Two placebo-controlled crossover studies in healthy subjects to evaluate gastric acid neutralization by an alginate-antacid formulation (Gaviscon Double Action). QPS Two placebo-controlled crossover studies in healthy subjects to evaluate gastric acid neutralization by an alginate-antacid formulation (Gaviscon Double Action). Read More ยป
The absolute bioavailability and the effect of food on a new magnesium lactate dehydrate extended-release caplet in healthy subjects QPS The absolute bioavailability and the effect of food on a new magnesium lactate dehydrate extended-release caplet in healthy subjects Read More ยป
Asenapine pharmacokinetics and tolerability in a pediatric population QPS Asenapine pharmacokinetics and tolerability in a pediatric population Read More ยป
Safety and clinical effect of i.v. infusion of cyclopropyl-methoxycarbonyl etomidate (ABP-700), a soft analogue of etomidate, in healthy subjects QPS Safety and clinical effect of i.v. infusion of cyclopropyl-methoxycarbonyl etomidate (ABP-700), a soft analogue of etomidate, in healthy subjects Read More ยป
A Phase 1, Single-center, Double-blind, Placebo-controlled Study in Healthy Subjects to Assess the Safety, Tolerability, Clinical Effects, and Pharmacokinetics-Pharmacodynamics of Intravenous Cyclopropyl-methoxycarbony lmetomidate (ABP-700) after a Single Ascending Bolus Dose QPS A Phase 1, Single-center, Double-blind, Placebo-controlled Study in Healthy Subjects to Assess the Safety, Tolerability, Clinical Effects, and Pharmacokinetics-Pharmacodynamics of Intravenous Cyclopropyl-methoxycarbony lmetomidate (ABP-700) after a Single Ascending Bolus Dose Read More ยป
ERS technical standard on bronchial challenge testing: general considerations and performance of methacholine challenge tests QPS ERS technical standard on bronchial challenge testing: general considerations and performance of methacholine challenge tests Read More ยป
Generic medications in precision medicine in asthma QPS Generic medications in precision medicine in asthma Read More ยป
Role of biologics targeting type 2 airway inflammation in asthma: what have we learned so far? QPS Role of biologics targeting type 2 airway inflammation in asthma: what have we learned so far? Read More ยป
