According to the World Health Organization, cardiovascular disease is the leading cause of death in the United States and worldwide. In fact, about 17.9 million people die from cardiovascular disease each year, accounting for an estimated 31 percent of deaths worldwide. Yet despite cardiovascular disease being a continual, significant threat to human health, investment in …
QPS Physician Nutte Van Belzen Wins 2019 Young Entrepreneur Award
Entrepreneur Nutte Van Belzen of CC Diagnostics recently won the 2019 Jonge Ondernemingsprijs (Young Entrepreneur Award). Van Belzen also happens to work as a part-time physician at QPS Netherlands, located in Groningen. A wonderful surprise, this award is a reflection of Van Belzen’s hard work and ambitious spirit. What is the Young Entrepreneur Award? The …
5xFAD Mice Offer Hope for Alzheimer’s Disease Research
Recently, the Shanghai-based company Green Valley announced approval of their drug candidate Oligomannate for clinical use in mild to moderate Alzheimer’s disease (AD) in China. This news made a big splash because nearly two decades have passed since the last approval of an Alzheimer’s drug. The successful approval of this drug was partially based on …
Small Molecule Drug Discovery Opening Doors for Chronic Disease Management
Although large molecule drug discovery has become more popular recently, small molecules have always acted as the basis for the majority of drug research and development and are expected to remain in demand in the years to come. In fact, one study estimates that the global market for small molecule drug discovery will grow at …
High Translational Value Biomarkers in Neurodegenerative Disease
Biomarkers are an emerging area of focus in neurodegenerative diseases. This new scrutiny has arisen because biomarkers may provide an important link between preclinical disease models and the evaluation of disease progression in patients. One of these biomarkers, neurofilament light chain (NF-L), a neuronal cytoplasmic protein, is increased in a variety of neuronal diseases due …
The Importance of Animal Welfare in Preclinical In Vivo Research
Until recently, many scientists were convinced that animal welfare and high-quality animal research were not compatible. Animal welfare was considered a nuisance that should be circumvented if possible, so scientists put in as little effort as possible. Fortunately, animal welfare experts refused to stop pushing the scientific community to pay attention to improvements in this …
Working with Families in Pediatric Clinical Drug Trials
When designing pediatric clinical drug trials, it’s important to work with the entire family to ensure the experience is convenient, comfortable, and rewarding. If certain factors are overlooked, families may drop out of a trial, making it difficult to complete a statistically relevant trial. From the recruiting process to the running of the trial, there …
Guidance for Scheduling Clinical Trials in Children
Children are not little adults, but due to a lack of pediatric clinical trials, children are often prescribed drugs that have only been approved for use in adults. Fortunately, more pediatric clinical trials are being conducted to study and approve more drugs for use in children. In some ways, clinical trials in children are identical to …
New Horizons for Patient Studies at QPS-NL
In the pharmaceutical and biotechnology industry more small and even virtual companies are established thereby changing the traditional way of working in early drug development. In the last decade there evolved a trend to obtain Proof of Concept (PoC) as fast as possible directly in patients instead of healthy subjects or as part of an …
QPS Neuropharmacology Announces Cooperation with the University of Bari Aldo Moro for Autism Spectrum Disorder R&D Project
QPS Neuropharmacology and the research group of Marcello Leopoldo from the University of Bari Aldo Moro, Italy, are collaborating on a funded research project related to autism spectrum disorder (ASD). Funding by the Austrian Research Promotion Agency (FFG) to perform the whole study within the frame of the industry-related PhD program (“Industrienahe Dissertation”) has been …
