Role of Intestinal P-Glycoprotein in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents QPS Role of Intestinal P-Glycoprotein in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents Read More »
Effect of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide], a Human Tumor Necrosis Factor a-Converting Enzyme Inhibitor, on the Disposition of Methotrexate: A transporter-Based Drug-Drug Interaction Case Study QPS Effect of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide], a Human Tumor Necrosis Factor a-Converting Enzyme Inhibitor, on the Disposition of Methotrexate: A transporter-Based Drug-Drug Interaction Case Study Read More »
Effects of tibolone on sulfatase pathway of estrogens metabolism and on growth of MCF-7 human breast tumors implanted in ovariectomized nude mice QPS Effects of tibolone on sulfatase pathway of estrogens metabolism and on growth of MCF-7 human breast tumors implanted in ovariectomized nude mice Read More »
Distribution of Radioactivity in Bone and Related Structures following Administration of [14C]Dalbavancin to New Zealand White Rabbits QPS Distribution of Radioactivity in Bone and Related Structures following Administration of [14C]Dalbavancin to New Zealand White Rabbits Read More »
Autoradiography: High-Resolution Molecular Imaging in Pharmaceutical Discovery and Development QPS Autoradiography: High-Resolution Molecular Imaging in Pharmaceutical Discovery and Development Read More »
Limited Interaction between Tacrolimus and P-Glycoprotein in the Rat Small Intestine QPS Limited Interaction between Tacrolimus and P-Glycoprotein in the Rat Small Intestine Read More »
Increased Hepatobiliary Clearance of Unconjugated Thyroxine Determines DMP 904-Induced Alterations in Thyroid Hormone Homeostasis in Rats QPS Increased Hepatobiliary Clearance of Unconjugated Thyroxine Determines DMP 904-Induced Alterations in Thyroid Hormone Homeostasis in Rats Read More »
ß-Cyclodextrin as a Suitable Solubilizing Agent for In Situ Absorption Study of Poorly Water-Soluble Drugs QPS ß-Cyclodextrin as a Suitable Solubilizing Agent for In Situ Absorption Study of Poorly Water-Soluble Drugs Read More »
Concurrent Induction and Mechanism-based Inactivation of CYP3A4 by an L-Valinamide Derivative QPS Concurrent Induction and Mechanism-based Inactivation of CYP3A4 by an L-Valinamide Derivative Read More »
Radiation Dose to Abdominal Organs of the Mouse due to 90Y in the Urinary Bladder QPS Radiation Dose to Abdominal Organs of the Mouse due to 90Y in the Urinary Bladder Read More »
Interaction of Ritonavir on Tissue Distribution of a [14C]L-Valinamide, a Potent Human Immunodeficiency Virus-1 protease Inhibitor, in Rats using Quantitative Whole-body Autoradiography QPS Interaction of Ritonavir on Tissue Distribution of a [14C]L-Valinamide, a Potent Human Immunodeficiency Virus-1 protease Inhibitor, in Rats using Quantitative Whole-body Autoradiography Read More »