DMPK

LC-TOF-MS methods to quantify siRNAs and major metabolites in plasma, urine and tissues.

QPS

LC-TOF-MS methods to quantify siRNAs and major metabolites in plasma, urine and tissues. Read More »

Metabolism, Excretion, and Pharmacokinetics of [14C]-Cefiderocol (S-649266), a Siderophore Cephalosporin, in Healthy Subjects Following Intravenous Administration

QPS

Metabolism, Excretion, and Pharmacokinetics of [14C]-Cefiderocol (S-649266), a Siderophore Cephalosporin, in Healthy Subjects Following Intravenous Administration Read More »

Pharmacokinetics, distribution, metabolism, and excretion of the dual reuptake inhibitor [14C]-nefopam in rats

QPS

Pharmacokinetics, distribution, metabolism, and excretion of the dual reuptake inhibitor [14C]-nefopam in rats Read More »

Autoradiography Techniques and Quantification of Drug Distribution

QPS

Autoradiography Techniques and Quantification of Drug Distribution Read More »

Metabolism and Disposition of Cabozantinib in Healthy Male Volunteers and Pharmacologic Characterization of Its Major Metabolites.

QPS

Metabolism and Disposition of Cabozantinib in Healthy Male Volunteers and Pharmacologic Characterization of Its Major Metabolites. Read More »

Absorption, Distribution, Metabolism, and Excretion of [14C]GDC-0449 (Vismodegib), an Orally Active Hedgehog Pathway Inhibitor, in Rats and Dogs: A Unique Metabolic Pathway via Pyridine Ring Opening

QPS

Absorption, Distribution, Metabolism, and Excretion of [14C]GDC-0449 (Vismodegib), an Orally Active Hedgehog Pathway Inhibitor, in Rats and Dogs: A Unique Metabolic Pathway via Pyridine Ring Opening Read More »

Autoradiography, MALDI-MS, and SIMS-MS Imaging in Pharmaceutical Discovery and Development

QPS

Autoradiography, MALDI-MS, and SIMS-MS Imaging in Pharmaceutical Discovery and Development Read More »

Efficacy of CMX001 against Herpes Simplex Virus Infections in Mice and Correlations with Drug Distribution Studies

QPS

Efficacy of CMX001 against Herpes Simplex Virus Infections in Mice and Correlations with Drug Distribution Studies Read More »

Autoradiography, MALDI-MS, and SIMS-MS Imaging in Pharmaceutical Discovery and Development

QPS

Autoradiography, MALDI-MS, and SIMS-MS Imaging in Pharmaceutical Discovery and Development Read More »

Efficacy of CMX001 against Herpes Simplex Virus Infections in Mice and Correlations with Drug Distribution Studies

QPS

Efficacy of CMX001 against Herpes Simplex Virus Infections in Mice and Correlations with Drug Distribution Studies Read More »

Criteria for selecting pharmacokinetic repeat study samples

QPS

Criteria for selecting pharmacokinetic repeat study samples Read More »

The Distribution Pattern of Intravenous [14C] Artesunate in Rat Tissues by Quantitative Whole-body Autoradiography and Tissue Dissection Techniques

QPS

The Distribution Pattern of Intravenous [14C] Artesunate in Rat Tissues by Quantitative Whole-body Autoradiography and Tissue Dissection Techniques Read More »