Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value QPS Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value Read More ยป
CD8 + T-cells Infiltrate Alzheimer’s Disease Brains and Regulate Neuronal- And Synapse-Related Gene Expression in APP-PS1 Transgenic Mice QPS CD8 + T-cells Infiltrate Alzheimer’s Disease Brains and Regulate Neuronal- And Synapse-Related Gene Expression in APP-PS1 Transgenic Mice Read More ยป
Transgene integration causes RARB downregulation in homozygous Tg4-42 mice. QPS Transgene integration causes RARB downregulation in homozygous Tg4-42 mice. Read More ยป
The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies. QPS The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies. Read More ยป
Plasma pharmacokinetic and metabolism of [18F]THK-5317 are dependent on sex. QPS Plasma pharmacokinetic and metabolism of [18F]THK-5317 are dependent on sex. Read More ยป
Effector function of anti-pyroglutamate-3 Aฮฒ antibodies affects cognitive benefit, glial activation and amyloid clearance in Alzheimer’s-like mice. QPS Effector function of anti-pyroglutamate-3 Aฮฒ antibodies affects cognitive benefit, glial activation and amyloid clearance in Alzheimer’s-like mice. Read More ยป
Characterization of the visceral and neuronal phenotype of 4L/PS-NA mice modeling Gaucher disease. QPS Characterization of the visceral and neuronal phenotype of 4L/PS-NA mice modeling Gaucher disease. Read More ยป
Correction: Further investigation of phenotypes and confounding factors of progressive ratio performance and feeding behavior in the BACHD rat model of Huntington disease. QPS Correction: Further investigation of phenotypes and confounding factors of progressive ratio performance and feeding behavior in the BACHD rat model of Huntington disease. Read More ยป
Hepatic and neuronal phenotype of NPC1โ/โ mice QPS Hepatic and neuronal phenotype of NPC1โ/โ mice Read More ยป
Development of GMP-1 a molecular chaperone network modulator protecting mitochondrial function and its assessment in fly and mice models of Alzheimer’s disease. QPS Development of GMP-1 a molecular chaperone network modulator protecting mitochondrial function and its assessment in fly and mice models of Alzheimer’s disease. Read More ยป
BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains. QPS BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains. Read More ยป
Phosphorylation of different tau sites during progression of Alzheimer’s disease. QPS Phosphorylation of different tau sites during progression of Alzheimer’s disease. Read More ยป
mTh1 driven expression of hTDP-43 results in typical ALS/FTLD neuropathological symptoms. QPS mTh1 driven expression of hTDP-43 results in typical ALS/FTLD neuropathological symptoms. Read More ยป
Large-Scale Oral Treatment Study with the Four Most Promising D3-Derivatives for the Treatment of Alzheimer’s Disease. QPS Large-Scale Oral Treatment Study with the Four Most Promising D3-Derivatives for the Treatment of Alzheimer’s Disease. Read More ยป
SEN1500, a novel oral amyloid-ฮฒ aggregation inhibitor, attenuates brain pathology in a mouse model of Alzheimer’s disease. QPS SEN1500, a novel oral amyloid-ฮฒ aggregation inhibitor, attenuates brain pathology in a mouse model of Alzheimer’s disease. Read More ยป
Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form. QPS Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form. Read More ยป
Glutaminyl Cyclase Inhibitor PQ912 improves cognition in mouse models of Alzheimer’s disease – studies on relation to effective target occupancy. QPS Glutaminyl Cyclase Inhibitor PQ912 improves cognition in mouse models of Alzheimer’s disease – studies on relation to effective target occupancy. Read More ยป
Early start of progressive motor deficits in Line 61 ฮฑ-synuclein transgenic mice. QPS Early start of progressive motor deficits in Line 61 ฮฑ-synuclein transgenic mice. Read More ยป
Early and progressive microstructural brain changes in mice overexpressing human ฮฑ-Synuclein detected by diffusion kurtosis imaging. QPS Early and progressive microstructural brain changes in mice overexpressing human ฮฑ-Synuclein detected by diffusion kurtosis imaging. Read More ยป
Quantitative evaluation of orofacial motor function in mice: The pasta gnawing test, a voluntary and stress-free behavior test. QPS Quantitative evaluation of orofacial motor function in mice: The pasta gnawing test, a voluntary and stress-free behavior test. Read More ยป
