Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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Donepezil
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 20 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Dementia and Alzheimer's Disease |
| Classification: | Drugs |
Donepezil
| Matrix: | Human Plasma |
| Assay Range: | 0.2 to 200 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | K2 EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Dementia and Alzheimer's Disease |
| Classification: | Drugs |
Doxazosin
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 20 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Doxazosin
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 25 ng/mL |
| Sample Volume: | 0.4 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Doxepin
Nor-doxepin
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 120 ng/mL 0.1 - 60 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antidepressant |
| Classification: | Drugs |
Doxepin
Nor-doxepin
| Matrix: | Human Plasma |
| Assay Range: | 0.3 - 180 ng/mL 0.3 - 60 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antidepressant |
| Classification: | Drugs |
Doxepin
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 60 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antidepressant |
| Classification: | Drugs |
Doxycycline
| Matrix: | Human Plasma |
| Assay Range: | 10 - 5,000 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drugs |
Doxycycline
| Matrix: | Human Plasma |
| Assay Range: | 20 - 2,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drugs |
Doxycycline
| Matrix: | Human Plasma |
| Assay Range: | 10 - 1,500 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drugs |
Duloxetine
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 200 ng/mL |
| Sample Volume: | 0.25 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Analgesic |
| Classification: | Drugs |
Dutasteride
| Matrix: | Human Plasma |
| Assay Range: | 0.05 - 50 ng/mL |
| Sample Volume: | 0.15 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Men's Health |
| Classification: | Drugs |
Dutasteride
| Matrix: | Human Plasma |
| Assay Range: | 100 - 7500 pg/mL |
| Sample Volume: | 0.3mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Men's Health |
| Classification: | Drugs |
Dutasteride
| Matrix: | Human Serum |
| Assay Range: | 0.05 - 50 ng/mL |
| Sample Volume: | 0.15 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Men's Health |
| Classification: | Drugs |
E-selectin
| Matrix: | Human Plasma |
| Assay Range: | 0.6 - 3,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biomarkers |
E-selectin
| Matrix: | Human Serum |
| Assay Range: | 0.6 - 3,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Inflammation |
| Classification: | Biomarkers |
E-Selectin (rs5361) Genotyping
| Matrix: | Human Whole Blood |
| Assay Range: | N/A |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -80 |
| Platform: | TaqMan; QuantStudio |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Genomic |
Edoxaban
| Matrix: | Human Plasma |
| Assay Range: | 2 - 1,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Oral Anticoagulant |
| Classification: | Drugs |
Efavirenz (EFV)
| Matrix: | Human Plasma |
| Assay Range: | 1 - 1,500 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
Efavirenz (EFV)
| Matrix: | Human Plasma |
| Assay Range: | 5 - 5,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
Efavirenz (EFV)
| Matrix: | Human Plasma |
| Assay Range: | 15 - 6,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
Eltrombopag
| Matrix: | Human Plasma |
| Assay Range: | 50 - 30,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Thrombopoietin |
| Classification: | Drugs |
Empagliflozin
| Matrix: | Human Plasma |
| Assay Range: | 1 - 800 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Endocrinology |
| Classification: | Drugs |
Empagliflozin
| Matrix: | Human Plasma |
| Assay Range: | 2 - 1,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Endocrinology |
| Classification: | Drugs |
Emtricitabine (FTC)
Tenofovir (TFV)
| Matrix: | Human Plasma |
| Assay Range: | 5 - 3,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
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