Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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Guaifenesin
| Matrix: | Human Plasma |
| Assay Range: | 10 - 6,000 ng/mL |
| Sample Volume: | 0.15 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Allergy |
| Classification: | Drugs |
High mobility group box protein 1 (HMGB-1)
| Matrix: | Human Whole Blood Supernatant |
| Assay Range: | 2.5 - 80 ng/mL |
| Sample Volume: | 0.02 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Inflammation |
| Classification: | Biomarkers |
Human IgG1 (PK)
| Matrix: | Cynomolgus Monkey Plasma |
| Assay Range: | 0.1 - 100 µg/mL |
| Sample Volume: | 0.005 mL |
| Anti-Coagulant: | K2EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | Immunocapture-LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Obesity |
| Classification: | Drugs |
Human IgG1 (PK)
| Matrix: | Cynomolgus Monkey Serum |
| Assay Range: | 0.1 - 100 µg/mL |
| Sample Volume: | 0.005 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -70 |
| Platform: | Immunocapture-LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Obesity |
| Classification: | Drugs |
Human IgG1 (PK)
| Matrix: | Rat Plasma |
| Assay Range: | 0.1 - 100 µg/mL |
| Sample Volume: | 0.005 mL |
| Anti-Coagulant: | K2EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | Immunocapture-LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Obesity |
| Classification: | Drugs |
Human IgG4 (PK)
| Matrix: | Cynomolgus Monkey Plasma |
| Assay Range: | 0.1 - 100 µg/mL |
| Sample Volume: | 0.005 mL |
| Anti-Coagulant: | K2EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | Immunocapture-LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Obesity |
| Classification: | Drugs |
Hydrochlorothiazide
| Matrix: | Human Plasma |
| Assay Range: | 4 - 350 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Hydrocodone
Codeine
Guaifenesin
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 100 ng/mL 0.3 - 300 ng/mL 5 - 5,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Narcotic Analgesic |
| Classification: | Drugs |
Hydrocodone
Hydromorphone
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 200 ng/mL 0.05 - 5 ng/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Narcotic Analgesic |
| Classification: | Drugs |
Hydrocodone
Hydromorphone
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 100 ng/mL 0.03 - 30 ng/mL |
| Sample Volume: | 0.25 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Narcotic Analgesic |
| Classification: | Drugs |
Hydrocodone
Hydromorphone
| Matrix: | Rat Plasma |
| Assay Range: | 0.05 - 100 ng/mL 0.1 - 100 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Narcotic Analgesic |
| Classification: | Drugs |
Ibandronate
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 100 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Bone Health |
| Classification: | Drugs |
Ibandronate
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 100 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Bone Health |
| Classification: | Drugs |
Ibrutinib
| Matrix: | Human Plasma |
| Assay Range: | 0.8 - 400 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Ibuprofen
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 40 µg/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | NSAID |
| Classification: | Drugs |
Ibuprofen
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 120 µg/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | NSAID |
| Classification: | Drugs |
Ibuprofen
| Matrix: | Human Plasma |
| Assay Range: | 1 - 125 µg/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | NSAID |
| Classification: | Drugs |
Ibuprofen
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 50 ug/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | NSAID |
| Classification: | Drugs |
Imatinib
Desmethyl Imatinib
| Matrix: | Human Plasma |
| Assay Range: | 50 - 5,000 ng/mL 25 - 500 ng/mL |
| Sample Volume: | 0.10 ml |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Imatinib
Desmethyl Imatinib
| Matrix: | Human Plasma |
| Assay Range: | 50 - 2,000 ng/mL 20 - 200 ng/mL |
| Sample Volume: | 0.20 ml |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Imatinib
| Matrix: | Human Plasma |
| Assay Range: | 15 - 8,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Imidapril
Imidaprilat
| Matrix: | Human Plasma |
| Assay Range: | 0.4 - 80 ng/mL 0.2 - 60 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Imidapril
Imidaprilate
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 50 ng/mL 0.5 - 50 ng/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Imipramine
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 150 ng/mL |
| Sample Volume: | 0.25 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antidepressant |
| Classification: | Drugs |
Indinavir (IDV)
Nelfinavir (NFV)
Saquinavir (SQV)
Amprenavir (APV)
| Matrix: | Human Plasma |
| Assay Range: | 1 - 1,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
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