Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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Irbesartan
| Matrix: | Human Plasma |
| Assay Range: | 50 - 6,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Irbesartan
| Matrix: | Human Plasma |
| Assay Range: | 5 - 2500 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Irinotecan (CTP11)
SN-38
| Matrix: | Human Plasma |
| Assay Range: | 2 - 4,000 ng/mL 2 - 4,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Iron (total)
Iron (free)
| Matrix: | Human Serum |
| Assay Range: | 2.00 - 5,000 ng/mL 2.00 - 150 ng/mL above native |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | ICP-MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Drugs |
Iron (total)
Iron (free)
| Matrix: | Human Serum Ultrafiltrate |
| Assay Range: | 2.00 - 5,000 ng/mL 2.00 - 150 ng/mL above native |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | ICP-MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Drugs |
Isoniazid
| Matrix: | Human Plasma |
| Assay Range: | 10 -4000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | Sodium Heparin |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drugs |
Isosorbide Mononitrate
| Matrix: | Human Plasma |
| Assay Range: | 10 - 4,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Itraconazole
Hydroxyl-Itraconazole
| Matrix: | Human Plasma |
| Assay Range: | 1 - 500 ng/mL 2 - 1,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antifungal |
| Classification: | Drugs |
Itraconazole
| Matrix: | Human Plasma |
| Assay Range: | 1 - 500 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antifungal |
| Classification: | Drugs |
Ivacaftor
| Matrix: | Human Plasma |
| Assay Range: | 2 - 2,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cystic Fibrosis |
| Classification: | Drugs |
Ketoconazole
| Matrix: | Human Plasma |
| Assay Range: | 20 - 10,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antifungal |
| Classification: | Drugs |
Ketorolac
| Matrix: | Human Plasma |
| Assay Range: | 20 - 4,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Analgesic |
| Classification: | Drugs |
Kidney injury molecule 1
(KIM-1)
| Matrix: | Human Urine |
| Assay Range: | 0.156 - 10.0 pg/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Oncology, Inflammation, Metabolic, Nephrology |
| Classification: | Biomarkers |
Lacosamide
| Matrix: | Human Plasma |
| Assay Range: | 40 - 12,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Anticonvulsant |
| Classification: | Drugs |
Lamivudine (3TC)
Tenofovir (TFV)
in presence of Dolutegravir (DTG), Efavirenz (EFV), and Emtricitabine (FTC)
| Matrix: | Human Plasma |
| Assay Range: | 15 - 6,000 ng/mL 2.5 - 1,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
Lamivudine (3TC)
Tenofovir (TFV)
| Matrix: | Human Plasma |
| Assay Range: | 15 - 6,000 ng/mL 2.5 - 1000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
Lamivudine (3TC)
Zalcitabine (ddC)
| Matrix: | Human Plasma |
| Assay Range: | 1 - 1,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
Lamotrigine
| Matrix: | Human Plasma |
| Assay Range: | 1 - 600 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Anticonvulsant |
| Classification: | Drugs |
Lamotrigine
| Matrix: | Human Plasma |
| Assay Range: | 5 - 2,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Anticonvulsant |
| Classification: | Drugs |
Lamotrigine
| Matrix: | Human Plasma |
| Assay Range: | 5 - 4,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Anticonvulsant |
| Classification: | Drugs |
Lamotrigine
| Matrix: | Human Plasma |
| Assay Range: | 20 - 3,500 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Anticonvulsant |
| Classification: | Drugs |
Lamotrigine
| Matrix: | Human Plasma |
| Assay Range: | 5 - 1,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Anticonvulsant |
| Classification: | Drugs |
Lansoprazole
| Matrix: | Human Plasma |
| Assay Range: | 5 - 2,250 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Gastrointestinal |
| Classification: | Drugs |
Lansoprazole
| Matrix: | Human Plasma |
| Assay Range: | 2 - 2,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Gastrointestinal |
| Classification: | Drugs |
Lapatinib
| Matrix: | Human Plasma |
| Assay Range: | 1 - 100 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
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