Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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Methamphetamine
| Matrix: | Human Plasma |
| Assay Range: | 0.05 - 50 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Stimulant |
| Classification: | Drugs |
Methocarbamol
| Matrix: | Human Plasma |
| Assay Range: | 50 - 30,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Muscle Relaxant |
| Classification: | Drugs |
Methotrexate
7-Hydroxy Methotrexate
| Matrix: | Human Plasma |
| Assay Range: | 1 - 500 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Immunosuppressant |
| Classification: | Drugs |
Methotrexate
| Matrix: | Monkey Serum |
| Assay Range: | 1 - 1,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Immunosuppressant |
| Classification: | Drugs |
Methyl Diethyldithiocarbamate (Methyl-DDTC)
| Matrix: | Human Plasma |
| Assay Range: | 0.25 - 250 ng/mL |
| Sample Volume: | 0.4 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antimutagen |
| Classification: | Drugs |
Methylphenidate
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 15 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Stimulant |
| Classification: | Drugs |
Methylphenidate
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 50 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Stimulant |
| Classification: | Drugs |
Methylprednisolone
| Matrix: | Human Plasma |
| Assay Range: | 4 - 800 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Anti-inflammatory |
| Classification: | Drugs |
Methylprednisolone
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 60 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Anti-inflammatory |
| Classification: | Drugs |
Metoclopramide
| Matrix: | Human Plasma |
| Assay Range: | 1 - 100 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiemetic |
| Classification: | Drugs |
Metoclopramide
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 100 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiemetic |
| Classification: | Drugs |
Metoclopramide
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 50 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiemetic |
| Classification: | Drugs |
Metoprolol
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 100 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Metoprolol
| Matrix: | Human Plasma |
| Assay Range: | 1 - 500 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Miconazole
| Matrix: | Human Plasma |
| Assay Range: | 50 - 20,000 pg/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antifungal |
| Classification: | Drugs |
Midazolam
1-OH Midazolam
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 100 ng/mL 0.1 - 100 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | Lithium Heparin |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Sedative |
| Classification: | Drugs |
Midazolam
1-OH-Midazolam
4-OH-Midazolam
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 100 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Sedative |
| Classification: | Drugs |
Midazolam
1-OH-midazolam
| Matrix: | Human Plasma |
| Assay Range: | 0.100 - 100 ng/mL |
| Sample Volume: | 0.100 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Sedative |
| Classification: | Drugs |
Midazolam
1’-Hydroxymidazolam
| Matrix: | Human Plasma |
| Assay Range: | 0.1 to 100 ng/mL 0.1 to 100 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | K2 EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Sedative |
| Classification: | Drugs |
Midodrine in presence of Desglymidodrine
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 50 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | alpha-adrenergic agonists |
| Classification: | Drugs |
Miglitol
| Matrix: | Human Plasma |
| Assay Range: | 30 - 3,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antidiabetic |
| Classification: | Drugs |
Mitiglinide
| Matrix: | Human Plasma |
| Assay Range: | 5 - 2,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Antidiabetic |
| Classification: | Drugs |
Modafinil
| Matrix: | Human Plasma |
| Assay Range: | 20 - 20,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Stimulant |
| Classification: | Drugs |
Monomethyl Fumarate
| Matrix: | Human Plasma |
| Assay Range: | 15 - 6000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Multiple Sclerosis |
| Classification: | Drugs |
Montelukast
| Matrix: | Human Plasma |
| Assay Range: | 2 - 800 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Allergy |
| Classification: | Drugs |
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