Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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TNF-α High Sensitivity
| Matrix: | Human Serum |
| Assay Range: | 0.5 - 32 pg/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
TNFα
| Matrix: | Human Serum |
| Assay Range: | 2.44 - 2,500 pg/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | ECL (MSD) (9plex) |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
TolbutamideCarboxytolbutamideHydroxytolbutamide
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 100 ug/mL 5 - 5,000 ng/mL2 - 2,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | K2 EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Anti-diabetic |
| Classification: | Biochemical Biomarkers |
TolbutamideCarboxytolbutamideHydroxytolbutamide
| Matrix: | Human Urine |
| Assay Range: | 5 - 2,500 ng/mL 0.3 - 150 ug/mL0.1 - 50 ug/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Anti-diabetic |
| Classification: | Biochemical Biomarkers |
Tolterodine5-Hydroxy Methyl Tolterodine
| Matrix: | Human Plasma |
| Assay Range: | 40 - 5,000 pg/mL 40 - 5,000 pg/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Bladder Relaxant |
| Classification: | Drug Assays |
Tramadol
| Matrix: | Human Plasma |
| Assay Range: | 2 - 400 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Narcotic Analgesic |
| Classification: | Drug Assays |
Trans PhytoandioneCis Phytonadione
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 1,000 ng/mL 0.5 - 150 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Vitamins |
| Classification: | Drug Assays |
Trastuzumab
| Matrix: | Human Serum |
| Assay Range: | 2,000 - 256,000 ng/mL |
| Sample Volume: | 0.01 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drug Assays |
Trastuzumab – NAb
| Matrix: | Human Serum |
| Assay Range: | N.Ap. |
| Sample Volume: | |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -70 |
| Platform: | ECL (MSD) |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drug Assays |
Trastuzumab – Total (PK)
| Matrix: | Human Serum |
| Assay Range: | 500 - 100,000 ng/mL |
| Sample Volume: | 0.01 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drug Assays |
Treprostinil
| Matrix: | Human Plasma |
| Assay Range: | 10 - 5,000 pg/mL |
| Sample Volume: | 0.4 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Triamcinolone Acetonide
| Matrix: | Human Plasma |
| Assay Range: | 20 - 4,000 pg/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Respiratory |
| Classification: | Drug Assays |
Triazolam
| Matrix: | Human Plasma |
| Assay Range: | 50 - 50,000 pg/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Sedative |
| Classification: | Drug Assays |
TrientineMAT
| Matrix: | Human Plasma |
| Assay Range: | 3 - 3,000 ng/mL 3 - 3,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Chelating Agent |
| Classification: | Drug Assays |
Triglycerides
| Matrix: | Human Serum |
| Assay Range: | 0.101 - 2.82 mmol/L |
| Sample Volume: | 0.02 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | Enzyme assay |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
UDP-glucuronosyltransferase, UGT1A1 (*1, *6, *28, *36, *37) Genotyping
| Matrix: | Human Whole Blood |
| Assay Range: | N.Ap. |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -80 |
| Platform: | Pyrosequencing |
| Site: | QPS-Delaware |
| CLIA: | Yes |
| Therapy Area: | Alzheimer's Disease |
| Classification: | Genomic Biomarkers |
UDP-glucuronosyltransferase, UGT1A1 (*7, *93) Genotyping
| Matrix: | Human Whole Blood |
| Assay Range: | N.Ap. |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -80 |
| Platform: | Pyrosequencing |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Genomic Biomarkers |
Valproic acid
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 40 µg/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Anticonvulsant |
| Classification: | Drug Assays |
Valproic acid
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 75 µg/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Anticonvulsant |
| Classification: | Drug Assays |
Valproic acid
| Matrix: | Human Plasma |
| Assay Range: | 0.500 - 100 µg/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Anticonvulsant |
| Classification: | Drug Assays |
Valsartan
| Matrix: | Human Plasma |
| Assay Range: | 20 - 15,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Valsartan
| Matrix: | Human Plasma |
| Assay Range: | 30 - 20,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Valsartan Sacubitril
| Matrix: | Human Plasma |
| Assay Range: | 16 - 10,000 ng/mL 20 - 12000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Valsartan Sacubitril
| Matrix: | Human Plasma |
| Assay Range: | 14 to 7000 ng/mL 10 to 5000ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
ValsartanHydrochlorothiazide
| Matrix: | Human Plasma |
| Assay Range: | 20 - 15,000 ng/mL 2.5 - 500 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
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