Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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ValsartanHydrochlorothiazide
| Matrix: | Human Plasma |
| Assay Range: | 20 - 5,000 ng/mL 1 - 200 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
VEGF
| Matrix: | Human Serum |
| Assay Range: | 62.5 - 4,000 pg/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
Venlafaxine
| Matrix: | Human Plasma |
| Assay Range: | 1 - 100 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Antidepressant |
| Classification: | Drug Assays |
Venlafaxine O-Desmethyl Venlafaxine
| Matrix: | Human Plasma |
| Assay Range: | 1 - 400 ng/mL 2 - 500 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antidepressant |
| Classification: | Drug Assays |
Vildagliptin Metformin
| Matrix: | Human Plasma |
| Assay Range: | 2 - 800 ng/mL 10 - 4000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Anti-diabetic |
| Classification: | Drug Assays |
VKORC1 (-1639G>A) Genotyping
| Matrix: | Human Whole Blood |
| Assay Range: | N/A |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -80 |
| Platform: | TaqMan |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Genomic Biomarkers |
VoriconazoleVoriconazole N-Oxide
| Matrix: | Human Plasma |
| Assay Range: | 20 - 20,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antifungal |
| Classification: | Drug Assays |
Warfarin
| Matrix: | Human Plasma |
| Assay Range: | 1 - 1,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Blood Thinner |
| Classification: | Drug Assays |
Warfarin, (R)-(+)-Warfarin, (S)-(-)-
| Matrix: | Human Plasma |
| Assay Range: | 5 - 2,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Blood Thinner |
| Classification: | Drug Assays |
Yttrium
| Matrix: | Rat Plasma |
| Assay Range: | 10.0 - 2,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | ICP-MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Drug Assays |
Yttrium
| Matrix: | Formulation |
| Assay Range: | 100 - 1,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | ICP-MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Drug Assays |
Zafirlukast
| Matrix: | Human Plasma |
| Assay Range: | 1 - 700 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Respiratory |
| Classification: | Drug Assays |
Zaleplon
| Matrix: | Human Plasma |
| Assay Range: | 0.3 - 50 ng/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Sedative |
| Classification: | Drug Assays |
Zaleplon
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 80 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Sedative |
| Classification: | Drug Assays |
Zidovudine (AZT) Lamivudine (3TC) Stavudine (D4T)
| Matrix: | Human Plasma |
| Assay Range: | 2 - 2,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drug Assays |
Ziprasidone
| Matrix: | Human Plasma |
| Assay Range: | 0.25 - 250 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antipsychotic |
| Classification: | Drug Assays |
Ziprasidone
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 250 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antipsychotic |
| Classification: | Drug Assays |
Zolpidem
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 300 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Sedative |
| Classification: | Drug Assays |
Zonisamide
| Matrix: | Human Plasma |
| Assay Range: | 10 - 3000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Anticonvulsant |
| Classification: | Drug Assays |
Zonisamide
| Matrix: | Human Serum |
| Assay Range: | 50 - 2,500 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Anticonvulsant |
| Classification: | Drug Assays |
Links to Relevant Documents
Testimonials
Thanks for the good news, I’m happy to see that within less than a month you will have developed and validated the assay. Good Job!
QPS CLIENT