Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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17-Desacetyl Norgestimate (Norelgestromin)
| Matrix: | Human Plasma |
| Assay Range: | 0.02 - 10 ng/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Birth Control |
| Classification: | Drugs |
17α-Ethynylestradiol
Levonorgestrel
| Matrix: | Human Plasma |
| Assay Range: | 5.00 - 500 pg/mL 200 - 20,000 pg/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Birth Control |
| Classification: | Drugs |
19-Norandrosterone
19-Norethiocholanolone
| Matrix: | Human Plasma |
| Assay Range: | 20 - 5,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Drugs |
4-Phenylbutyric acid
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 200 µg/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
5-Fluorouracil (5-FU)
| Matrix: | Human Plasma |
| Assay Range: | 5 - 3,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
6-Methoxy-2-Naphthylacetic acid (Nebumetane)
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 75 µg/ml |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | HPLC-UV |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Analgesic |
| Classification: | Drugs |
Abacavir
Dolutegravir
Lamivudine
| Matrix: | Human Plasma |
| Assay Range: | 4 - 2200 ng/mL 3 - 1650 ng/mL 2 - 1100 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
Abacavir (ABC)
Lamivudine (3TC)
| Matrix: | Human Plasma |
| Assay Range: | 20 - 12,000 ng/mL 15 - 6,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
Abacavir (ABC)
| Matrix: | Human Plasma |
| Assay Range: | 20 - 10,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
Abacavir (ABC)
| Matrix: | Human Plasma |
| Assay Range: | 5 - 5,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
Abeta (Aß) Total
| Matrix: | Human Plasma |
| Assay Range: | 100 - 8,000 pg/mL |
| Sample Volume: | 0.025 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | ECL (MSD) |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Alzheimer's Disease |
| Classification: | Biomarkers |
Abeta (Aß) Total
| Matrix: | Human CSF |
| Assay Range: | 200 - 10,000 pg/mL |
| Sample Volume: | 0.025 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ECL (MSD) |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Alzheimer's Disease |
| Classification: | Biomarkers |
Abiraterone
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 500 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | Fluoride Oxalate |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Abiraterone
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 250 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Abiraterone
| Matrix: | Human Plasma |
| Assay Range: | 1 - 1,000 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Acetaminophen
Dextromethorphan
Dextrorphan
| Matrix: | Dog Plasma |
| Assay Range: | 1 - 500 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Analgesic |
| Classification: | Drugs |
Acetaminophen
Dextromethorphan
Dextrorphan
| Matrix: | Rat Plasma |
| Assay Range: | 10 - 5,000 ng/mL 1 - 500 ng/mL 1 - 500 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Respiratory |
| Classification: | Drugs |
Acetaminophen
Propoxyphene
| Matrix: | Human Plasma |
| Assay Range: | 50 - 2,000 ng/mL 1 - 400 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Analgesic |
| Classification: | Drugs |
Acetaminophen
| Matrix: | Human Plasma |
| Assay Range: | 50 - 30,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Analgesic |
| Classification: | Drugs |
Acetaminophen
| Matrix: | Human Plasma |
| Assay Range: | 75 - 20,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Analgesic |
| Classification: | Drugs |
Acetazolamide
| Matrix: | Human Plasma |
| Assay Range: | 50 - 30,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiseizure |
| Classification: | Drugs |
Acetazolamide
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 50 µg/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiseizure |
| Classification: | Drugs |
Acetylsalicyclic acid
Dipyridamole
Salicyclic Acid
| Matrix: | Human Plasma |
| Assay Range: | 2 - 500 ng/mL 20 - 4,000 ng/mL 40 - 4,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Analgesic |
| Classification: | Drugs |
Acetylsalicylic Acid
Salicylic Acid
| Matrix: | Human Plasma |
| Assay Range: | 10 - 2,500 ng/mL 50 - 10,000 ng/mL |
| Sample Volume: | 0.4 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Analgesic |
| Classification: | Drugs |
Acetylsalicylic Acid
Salicylic Acid
| Matrix: | Human Plasma |
| Assay Range: | 50 - 2,500 ng/mL 500 - 7,000 ng/mL |
| Sample Volume: | 0.25 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Analgesic |
| Classification: | Drugs |
Links to Relevant Documents
Testimonials
Thanks for the good news, I’m happy to see that within less than a month you will have developed and validated the assay. Good Job!
QPS CLIENT