Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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Methylphenidate
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 15 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Stimulant |
| Classification: | Drug Assays |
Methylphenidate
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 50 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Stimulant |
| Classification: | Drug Assays |
Methylprednisolone
| Matrix: | Human Plasma |
| Assay Range: | 4 - 800 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Antiinflammatory |
| Classification: | Drug Assays |
Metoclopramide
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 50 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiemetic |
| Classification: | Drug Assays |
Metoclopramide
| Matrix: | Human Plasma |
| Assay Range: | 1 - 100 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiemetic |
| Classification: | Drug Assays |
Metoclopramide
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 100 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiemetic |
| Classification: | Drug Assays |
Metoprolol
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 80 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Metoprolol
| Matrix: | Human Plasma |
| Assay Range: | 2 - 500 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Midazolam 1’-Hydroxymidazolam
| Matrix: | Human Plasma |
| Assay Range: | 0.1 to 100 ng/mL 0.1 to 100 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | K2 EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Sedative |
| Classification: | Drug Assays |
Midazolam1-OH Midazolam
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 100 ng/mL 0.1 - 100 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | Lithium Heparin |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Sedative |
| Classification: | Drug Assays |
Midazolam1-OH-midazolam
| Matrix: | Human Plasma |
| Assay Range: | 0.100 - 100 ng/mL |
| Sample Volume: | 0.100 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Sedative |
| Classification: | Drug Assays |
Midazolam1-OH-Midazolam
| Matrix: | Human Whole Blood |
| Assay Range: | 0.100 - 100 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Sedative |
| Classification: | Drug Assays |
Midazolam1-OH-Midazolam
| Matrix: | Human Dried Blood Spots |
| Assay Range: | 0.100 - 100 ng/mL |
| Sample Volume: | 0.02 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Sedative |
| Classification: | Drug Assays |
Midazolam1-OH-Midazolam4-OH-Midazolam
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 100 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Sedative |
| Classification: | Drug Assays |
Miglitol
| Matrix: | Human Plasma |
| Assay Range: | 30 - 3,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Anti-diabetic |
| Classification: | Drug Assays |
Mitiglinide
| Matrix: | Human Plasma |
| Assay Range: | 5 - 2,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Anti-diabetic |
| Classification: | Drug Assays |
Modafinil
| Matrix: | Human Plasma |
| Assay Range: | 20 - 20,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Stimulant |
| Classification: | Drug Assays |
Monomethyl Fumarate
| Matrix: | Human Plasma |
| Assay Range: | 15 - 6,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Multiple Sclerosis |
| Classification: | Drug Assays |
Montelukast
| Matrix: | Human Plasma |
| Assay Range: | 2 - 800 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Allergy |
| Classification: | Drug Assays |
Montelukast
| Matrix: | Human Plasma |
| Assay Range: | 2 - 400 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Allergy |
| Classification: | Drug Assays |
Morphine
| Matrix: | Mouse Plasma |
| Assay Range: | 0.2 - 500 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Narcotic Analgesic |
| Classification: | Drug Assays |
Morphine
Morphine 3-glucuronide
Morphine 6-glucuronide
Morphine 3-glucuronide
Morphine 6-glucuronide
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 50 ng/mL 10 - 1,000 ng/mL 1 - 100 mg/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Narcotic Analgesic |
| Classification: | Drug Assays |
Moxifloxacin
| Matrix: | Human Plasma |
| Assay Range: | 25 - 5,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drug Assays |
Moxifloxacin
| Matrix: | Human Plasma |
| Assay Range: | 20 - 7,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drug Assays |
MT-RNR1 (1555A>G) and MT-TS1 (3243A>G) Mitochondrial DNA Genotyping
| Matrix: | Human Whole Blood |
| Assay Range: | N.Ap. |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -80 |
| Platform: | Pyrosequencing |
| Site: | QPS-Delaware |
| CLIA: | |
| Therapy Area: | |
| Classification: | Genomic Biomarkers |
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