Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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Neurofilament Light Chain (NFL)
| Matrix: | Human CSF |
| Assay Range: | 100 - 10,000 pg/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | neurodegenerative |
| Classification: | Biomarkers |
Neutrophil Gelatinase-Associated Lipocalin (NGAL)
| Matrix: | Human Urine |
| Assay Range: | 0.156 - 10.0 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Oncology, Inflammation, Immunology |
| Classification: | Biomarkers |
Nevirapine (NFV)
| Matrix: | Human Plasma |
| Assay Range: | 15 - 5,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
Nicorandil
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 100 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Nifedipine
| Matrix: | Human Plasma |
| Assay Range: | 1 - 400 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Nilotinib
| Matrix: | Human Plasma |
| Assay Range: | 2 - 2,500 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Nimesulide
| Matrix: | Human Plasma |
| Assay Range: | 100 - 10,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | NSAID |
| Classification: | Drugs |
Nintedanib
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 50 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Respiratory |
| Classification: | Drugs |
Nintedanib
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 60 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Respiratory |
| Classification: | Drugs |
Nirmaltrelvir
| Matrix: | Human Plasma |
| Assay Range: | 15 - 6,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiviral |
| Classification: | Drugs |
Nisoldipine
| Matrix: | Human Plasma |
| Assay Range: | 10 - 3000 pg/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Nisoldipine
| Matrix: | Human Plasma |
| Assay Range: | 75 - 20,000 pg/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Nitisinone
| Matrix: | Human Serum |
| Assay Range: | 10 - 8000 ng/mL |
| Sample Volume: | 0.05mL |
| Anti-Coagulant: | NA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Genetic metabolic disorder |
| Classification: | Drugs |
Nitrofurantoin
| Matrix: | Human Plasma |
| Assay Range: | 0.75 - 500 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drugs |
Nitrofurantoin
| Matrix: | Human Plasma |
| Assay Range: | 5 - 1,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drugs |
Nitrofurantoin
| Matrix: | Human Plasma |
| Assay Range: | 1 - 1,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drugs |
Norethindrone
| Matrix: | Human Plasma |
| Assay Range: | 0.05 to 10 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Women's Health |
| Classification: | Drugs |
Norgestimate
Norgestrel
| Matrix: | Human Plasma |
| Assay Range: | 50 - 50,000 pg/mL 20 - 20,000 pg/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Women's Health |
| Classification: | Drugs |
Nortriptyline
10-OH-Nortriptyline
| Matrix: | Human Plasma |
| Assay Range: | 0.18 - 50 ng/mL 0.3 - 80 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antidepressant |
| Classification: | Drugs |
Obeticholic Acid
Glyco obeticholic acid
Tauro obeticholic acid
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 120 ng/mL 0.4 - 120 ng/mL 0.2 - 60 ng/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Farnesoid-X receptor (FXR) agonist |
| Classification: | Drugs |
Olaparib
| Matrix: | Human Plasma |
| Assay Range: | 50- 25,000 ng/mL |
| Sample Volume: | 0.05mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Olmesartan
| Matrix: | Human Plasma |
| Assay Range: | 10- 3000 ng/mL |
| Sample Volume: | 0.1mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Olmesartan
| Matrix: | Human Plasma |
| Assay Range: | 10- 2000 ng/mL |
| Sample Volume: | 0.1mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Olsalazine in presence of Mesalamine
| Matrix: | Human Plasma |
| Assay Range: | 8 - 2,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Anti-inflammatory |
| Classification: | Drugs |
Omeprazole
| Matrix: | Human Plasma |
| Assay Range: | 20 - 2,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Gastrointestinal |
| Classification: | Drugs |
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