Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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Ribavirin
| Matrix: | Human Plasma |
| Assay Range: | 10 - 10,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiviral - HCV |
| Classification: | Drugs |
Rifabutin
25-O-Deacetyl Rifabutin
| Matrix: | Human Plasma |
| Assay Range: | 1 - 1,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drugs |
Rifampin
| Matrix: | Human Plasma |
| Assay Range: | 20 - 10,000 pg/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drugs |
Rifampin
| Matrix: | Human Whole Blood |
| Assay Range: | 20 - 10,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drugs |
Rifampin
| Matrix: | Human Whole Blood |
| Assay Range: | 1 - 100 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drugs |
Rilpivirine
| Matrix: | Human Plasma |
| Assay Range: | 1 - 500 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
Rilpivirine
| Matrix: | Human Plasma |
| Assay Range: | 0.7 - 350 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
Riluzole
| Matrix: | Human Plasma |
| Assay Range: | 1 - 500 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | ALS |
| Classification: | Drugs |
Riociguat
| Matrix: | Human Plasma |
| Assay Range: | 1 - 250 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Risperidone
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 50 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Antipsychotic |
| Classification: | Drugs |
Risperidone
| Matrix: | Human Plasma |
| Assay Range: | 0.25 - 25 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antipsychotic |
| Classification: | Drugs |
Ritonavir
| Matrix: | Human Plasma |
| Assay Range: | 5 - 2,500 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
Ritonavir (RTV)
Saquinavir (SQV)
| Matrix: | Human Plasma |
| Assay Range: | 1 - 1,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
Rituximab (ADA)
| Matrix: | Human Serum |
| Assay Range: | N/A |
| Sample Volume: | 0.01 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ECL (MSD) |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Rituximab (ADA)
| Matrix: | Human Serum |
| Assay Range: | N/A |
| Sample Volume: | 0.016 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Rituximab (Nab)
| Matrix: | Human Serum |
| Assay Range: | N/A |
| Sample Volume: | 0.02 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | Cell-Based |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Rituximab (PK)
| Matrix: | Human Serum |
| Assay Range: | 100 - 5,000 ng/mL |
| Sample Volume: | 0.01 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Rituximab (PK)
| Matrix: | Human Serum |
| Assay Range: | 90 - 2,000 ng/mL |
| Sample Volume: | 0.01 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Ritxumab (PK)
| Matrix: | Human Serum |
| Assay Range: | 90 - 60,000 ng/mL |
| Sample Volume: | 0.01 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | Gyrolab |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Rivaroxaban
| Matrix: | Human Plasma |
| Assay Range: | 1 - 800 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Oral Anticoagulant |
| Classification: | Drugs |
Rivastigmine
| Matrix: | Human Plasma |
| Assay Range: | 50 - 25,000 pg/mL |
| Sample Volume: | 0.075 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Parkinson's Disease |
| Classification: | Drugs |
Rivastigmine
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 25 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Parkinson's Disease |
| Classification: | Drugs |
Rivastigmine
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 60 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Parkinson's Disease |
| Classification: | Drugs |
Rizatriptan
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 80 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Migraine |
| Classification: | Drugs |
Ropinirole
| Matrix: | Human Plasma |
| Assay Range: | 25 - 1,000 pg/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Dopamine Promoter and Parkinson's Disease |
| Classification: | Drugs |
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