Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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Rosuvastatin
| Matrix: | Human Plasma |
| Assay Range: | 50 - 15,000 pg/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Rosuvastatin in presence of Aspirin and Salicylic acid
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 70 ng/mL |
| Sample Volume: | 0.4 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
S-100B
| Matrix: | Human Serum |
| Assay Range: | 50 - 2,000 pg/mL |
| Sample Volume: | 0.06 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
S-Amlodipine
| Matrix: | Human Plasma |
| Assay Range: | 50 - 15,000 pg/mL |
| Sample Volume: | 0.3mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Salicylic Acid in presence of Aspirin
| Matrix: | Human Plasma |
| Assay Range: | 200 - 14,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | NSAID |
| Classification: | Drug Assays |
Saxagliptin 5-OH-Saxagliptin in presence of Dapagliflozin
| Matrix: | Human Plasma |
| Assay Range: | 0.4 - 100 ng/mL 0.8 - 200 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Anti-diabetic |
| Classification: | Drug Assays |
Saxagliptin 5-OH-Saxagliptin in presence of Metformin
| Matrix: | Human Plasma |
| Assay Range: | 0.4 - 100 ng/mL 0.8 - 200 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Anti-diabetic |
| Classification: | Drug Assays |
Scopolamine
| Matrix: | Human Plasma |
| Assay Range: | 5 - 5,000 pg/mL |
| Sample Volume: | 0.15 mL |
| Anti-Coagulant: | K2 EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiemetic |
| Classification: | Drug Assays |
Sertraline
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 200 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antidepressant |
| Classification: | Drug Assays |
Sertraline
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 20 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Antidepressant |
| Classification: | Drug Assays |
Sertraline
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 200 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antidepressant |
| Classification: | Drug Assays |
Sertraline
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 80 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antidepressant |
| Classification: | Drug Assays |
Serum Amyloid A (SAA)
| Matrix: | Human Plasma |
| Assay Range: | 0.0696 - 218 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | ECL (MSD) |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
SHBG
| Matrix: | Human Serum |
| Assay Range: | 2 - 180 nmol/L |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | Immulite |
| Site: | QPS-NL |
| CLIA: | |
| Therapy Area: | |
| Classification: | Biochemical Biomarkers |
Sildenafil
| Matrix: | Human Plasma |
| Assay Range: | 1 - 1000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Sodium Heparin |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Vasodilator |
| Classification: | Drug Assays |
SildenafilN-Desmethyl Sildenafil
| Matrix: | Human Plasma |
| Assay Range: | 5 - 1,500 ng/mL 5 - 700 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Vasodilator |
| Classification: | Drug Assays |
SildenafilN-Desmethyl Sildenafil
| Matrix: | Human Plasma |
| Assay Range: | 1 - 1,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Vasodilator |
| Classification: | Drug Assays |
Silver
| Matrix: | Formulation |
| Assay Range: | 10.0 - 1,000 ng/mL |
| Sample Volume: | 125 µL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | 2 - 8 |
| Platform: | ICP-MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Drug Assays |
Silver
| Matrix: | Solid Samples |
| Assay Range: | 10.0 - 1,000 ng/mL |
| Sample Volume: | 250 mg |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | 2 - 8 |
| Platform: | ICP-MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Drug Assays |
Simvastatin
Simvastatin Acid
Simvastatin Acid
| Matrix: | Human Plasma |
| Assay Range: | 0.05 - 10 ng/mL 0.02 - 4 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Simvastatin
Simvastatin Hydroxy Acid
Simvastatin Hydroxy Acid
| Matrix: | Human Plasma |
| Assay Range: | 0.250 - 75 ng/mL 0.2 - 50 ng/mL |
| Sample Volume: | 0.25 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Simvastatin
Simvastatin Hydroxy Acid
Simvastatin Hydroxy Acid
| Matrix: | Human Plasma |
| Assay Range: | 0.250 - 125 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Simvastatin
Simvastatin Hydroxy Acid
Simvastatin Hydroxy Acid
| Matrix: | Human Plasma |
| Assay Range: | 0.05 - 25 ng/mL 0.02 - 10 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Sirolimus
| Matrix: | Human Whole Blood |
| Assay Range: | 0.2 - 100 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Immunosuppressant |
| Classification: | Drug Assays |
Sirolimus
| Matrix: | Human Whole Blood |
| Assay Range: | 0.5 - 60 ng/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Immunosuppressant |
| Classification: | Drug Assays |
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