Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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Testosterone
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 200 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | Sodium EDTA Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Men's Health |
| Classification: | Drugs |
Testosterone
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 200 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Men's Health |
| Classification: | Drugs |
Testosterone
| Matrix: | Human Serum |
| Assay Range: | 0.500 - 50.0 ng/mL |
| Sample Volume: | 0.25 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Men's Health |
| Classification: | Drugs |
Testosterone
| Matrix: | Human Serum |
| Assay Range: | 0.05 - 25.0 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Men's Health |
| Classification: | Drugs |
Testosterone (bioavailable)
| Matrix: | Human Serum |
| Assay Range: | 0.100 - 25.0 ng/mL |
| Sample Volume: | 0.25 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Men's Health |
| Classification: | Drugs |
Tetrabenazine
a-dihydrotetrabenazine
b-dihydrotetrabenazine
| Matrix: | Human plasma |
| Assay Range: | 0.1 - 50 ng/mL 0.5 - 250 ng/mL 0.5 - 250 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | CNS and Huntington's Disease |
| Classification: | Drugs |
Ticagrelor
| Matrix: | Human Plasma |
| Assay Range: | 2.5 - 1500 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiplatelet |
| Classification: | Drugs |
Tinidazole
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 100 µg/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drugs |
Tiotropium
| Matrix: | Human Plasma |
| Assay Range: | 0.100 - 50.0 pg/mL |
| Sample Volume: | 0.4 mL |
| Anti-Coagulant: | NaF/K2EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Respiratory |
| Classification: | Drugs |
Tipranavir (TPV)
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 112.5 µg/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiviral - HIV |
| Classification: | Drugs |
Tizanidine
| Matrix: | Human Plasma |
| Assay Range: | 1 - 500 ng/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Muscle Relaxant |
| Classification: | Drugs |
TNF-α
| Matrix: | Human Plasma |
| Assay Range: | 16 - 1,000 pg/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | Citrate EDTA Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Oncology, Inflammation |
| Classification: | Biomarkers |
TNF-α
| Matrix: | Human Serum |
| Assay Range: | 16 - 1,000 pg/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Oncology, Inflammation |
| Classification: | Biomarkers |
TNF-α
| Matrix: | Human Whole Blood Supernatant |
| Assay Range: | 6.2 - 459 pg/mL |
| Sample Volume: | 0.4 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Oncology, Inflammation |
| Classification: | Biomarkers |
TNF-α
| Matrix: | Human Serum |
| Assay Range: | 20 - 4,000 pg/mL |
| Sample Volume: | 0.06 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | Luminex |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Oncology, Inflammation |
| Classification: | Biomarkers |
TNF-α High Sensitivity
| Matrix: | Human Plasma |
| Assay Range: | 0.7 - 40,000 pg/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | Citrate |
| Storage Temperature (°C): | -20 |
| Platform: | ECL (MSD) |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Oncology, Inflammation |
| Classification: | Biomarkers |
TNF-α High Sensitivity
| Matrix: | Human Serum |
| Assay Range: | 0.5 - 32 pg/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Oncology, Inflammation |
| Classification: | Biomarkers |
Tofacitinib
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 120 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antirheumatic |
| Classification: | Drugs |
Tolbutamide
Carboxytolbutamide
Hydroxytolbutamide
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 100 μg/mL 5 - 5,000 ng/mL 2 - 2,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | K2 EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antidiabetic |
| Classification: | Drugs |
Tolbutamide
Carboxytolbutamide
Hydroxytolbutamide
| Matrix: | Human Urine |
| Assay Range: | 5 - 2,500 ng/mL 0.3 - 150 μg/mL 0.1 - 50 μg/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antidiabetic |
| Classification: | Drugs |
Tolterodine
5-Hydroxy Methyl Tolterodine
| Matrix: | Human Plasma |
| Assay Range: | 40 - 5,000 pg/mL 40 - 5,000 pg/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Bladder Relaxant |
| Classification: | Drugs |
Tramadol
| Matrix: | Human Plasma |
| Assay Range: | 2 - 400 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Narcotic Analgesic |
| Classification: | Drugs |
Trametinib
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 40 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Trans Phytonadione
Cis Phytonadione
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 120 ng/mL 0.2 - 25 ng/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Vitamins |
| Classification: | Drugs |
Trans Phytonadione
Cis Phytonadione
| Matrix: | Human Plasma |
| Assay Range: | 1 - 500 ng/mL 1 - 100 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Vitamins |
| Classification: | Drugs |
Links to Relevant Documents
Testimonials
Thanks for the good news, I’m happy to see that within less than a month you will have developed and validated the assay. Good Job!
QPS CLIENT