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Improved Bioavailability of Montelukast through a Novel Oral Mucoadhesive Film in Humans and Mice

Johanna Michael, Diana Bessa de Sousa, Justin Conway, Erick Gonzalez-Labrada, Rodolphe Obeid, Julia Tevini, Thomas Felder, Birgit Hutter-Paier, Horst Zerbe, Nadine Paiement, Ludwig Aigner

Pharmaceutics. 2020 Dec 23;13(1):E12. doi: 10.3390/pharmaceutics13010012.

Constant Levels of Tau Phosphorylation in the Brain of htau Mice

Joerg Neddens, Magdalena Daurer, Tina Loeffler, Saioa Alzola Aldamizetxebarria, Stefanie Flunkert, Birgit Hutter-Paier

Front Mol Neurosci 2020 Aug 28;13:136. doi: 10.3389/fnmol.2020.00136. eCollection 2020. 

Development and validation of an LC-MS/MS method for simultaneous quantification of co-administered trastuzumab and pertuzumab

Sandor Schokker, Fabrizia Fusetti, Francesco Bonardi, Remco J. Molenaar, Ron A.A. Mathôt, and Hanneke W.M. van Laarhoven

mAbs (August 2020)

Correlation of Pyroglutamate Amyloid β and Ptau Ser202/Thr205 Levels in Alzheimer’s Disease and Related Murine Models

Joerg Neddens, Magdalena Daurer, Stefanie Flunkert, Kerstin Beutl, Tina Loeffler, Lauren Walker, Johannes Attems, Birgit Hutter-Paier

PLoS One. 2020 Jul 9;15(7):e0235543. doi: 10.1371/journal.pone.0235543. eCollection 2020.

Validation of Behavioral Phenotypes in the BACHD Rat Model

Arianna Novati, Giuseppe Manfré, Stefanie Flunkert, Johanneke E Van der Harst, Judith R Homberg, Robert Wronski, Huu Phuc Nguyen

Behav Brain Res. 2020 Jun 20;112783. doi: 10.1016/j.bbr.2020.112783.

Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value

Tina Loeffler, Irene Schilcher, Stefanie Flunkert, and Birgit Hutter-Paier

Front. Neurosci., 11 June 2020

CD8 + T-cells Infiltrate Alzheimer’s Disease Brains and Regulate Neuronal- And Synapse-Related Gene Expression in APP-PS1 Transgenic Mice

M S Unger, E Li, L Scharnagl, R Poupardin, B Altendorfer, H Mrowetz, B Hutter-Paier, T M Weiger, M T Heneka, J Attems, L Aigner

Brain Behav Immun 2020 May 29;S0889-1591(19)31573-9. doi: 10.1016/j.bbi.2020.05.070.

Transgene integration causes RARB downregulation in homozygous Tg4-42 mice.

Hinteregger B, Loeffler T, Flunkert S, Neddens J, Birner-Gruenberger R, Bayer TA, Madl T, Hutter-Paier B.

Sci Rep. 2020 Apr 14;10(1):6377. doi: 10.1038/s41598-020-63512-8.

The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies.

Marschallinger J, Altendorfer B, Rockenstein E, Holztrattner M, Garnweidner-Raith J, Pillichshammer N, Leister I, Hutter-Paier B, Strempfl K, Unger MS, Chishty M, Felder T, Johnson M, Attems J, Masliah E, Aigner L.

Neurotherapeutics (February 2020)

Plasma pharmacokinetic and metabolism of [18F]THK-5317 are dependent on sex.

Mairinger S, Filip T, Sauberer M, Flunkert S, Wanek T, Stanek J, Furtner S, Hutter-Paier B, Okamura N, Kuntner C.

Nucl Med Biol. (January 2020)

Effector function of anti-pyroglutamate-3 Aβ antibodies affects cognitive benefit, glial activation and amyloid clearance in Alzheimer’s-like mice.

Crehan H, Liu B, Kleinschmidt M, Rahfeld JU, Le KX, Caldarone BJ, Frost JL, Hettmann T, Hutter-Paier B, O’Nuallain B, Park MA, DiCarli MF, Lues I, Schilling S, Lemere CA

Alzheimers Res Ther. (January 2020)

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