Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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Guaifenesin
| Matrix: | Human Plasma |
| Assay Range: | 10 - 6,000 ng/mL |
| Sample Volume: | 0.15 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Allergy |
| Classification: | Drug Assays |
Guaifenesin Pseudoephedrine
| Matrix: | Human Plasma |
| Assay Range: | 10 - 6,000 ng/mL 2 - 800 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Allergy |
| Classification: | Drug Assays |
Guaifenesin
Pseudoephedrine
Pseudoephedrine
| Matrix: | Human Plasma |
| Assay Range: | 10 - 5,000 ng/mL 2 - 750 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Allergy |
| Classification: | Drug Assays |
Haloperidol
| Matrix: | Human Plasma |
| Assay Range: | 0.100 - 100 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Antipsychotic |
| Classification: | Drug Assays |
High mobility group box protein 1 (HMGB-1)
| Matrix: | Human Whole Blood Supernatant |
| Assay Range: | 2.5 - 80 ng/mL |
| Sample Volume: | 0.02 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
HMGB-1
| Matrix: | Human Whole Blood Supernatant |
| Assay Range: | 2.5 - 80 ng/mL |
| Sample Volume: | 0.02 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | |
| Therapy Area: | |
| Classification: | Biochemical Biomarkers |
Homovanillic acid
| Matrix: | Human CSF |
| Assay Range: | 10.0 - 1,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
Human Growth Hormone (GH)
| Matrix: | Human Serum |
| Assay Range: | 0.05 - 40 ng/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | Immulite |
| Site: | QPS-NL |
| CLIA: | |
| Therapy Area: | |
| Classification: | Biochemical Biomarkers |
Human IgG1
| Matrix: | Rat Serum |
| Assay Range: | 50 - 5,000 ng/mL |
| Sample Volume: | 0.005 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
Human IgG1
| Matrix: | Mouse Serum |
| Assay Range: | 50 - 5,000 ng/mL |
| Sample Volume: | 0.005 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
Hydrochlorothiazide
| Matrix: | Human Plasma |
| Assay Range: | 4 - 350 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Hydrocodone
Codeine
Guaifenesin
Codeine
Guaifenesin
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 100 ng/mL0.3 - 300 ng/mL5 - 5,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Narcotic Analgesic |
| Classification: | Drug Assays |
Hydrocodone
Hydromorphone
Hydromorphone
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 200 ng/mL 0.05 - 5 ng/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Narcotic Analgesic |
| Classification: | Drug Assays |
Hydrocodone
Hydromorphone
Hydromorphone
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 100 ng/mL0.03 - 30 ng/mL |
| Sample Volume: | 0.25 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Narcotic Analgesic |
| Classification: | Drug Assays |
Hydrocodone
Hydromorphone
Hydromorphone
| Matrix: | Rat Plasma |
| Assay Range: | 0.05 - 100 ng/mL 0.1 - 100 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Narcotic Analgesic |
| Classification: | Drug Assays |
Ibandronate
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 100 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Bone Health |
| Classification: | Drug Assays |
Ibandronate
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 100 ng/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Bone Health |
| Classification: | Drug Assays |
Ibrutinib
| Matrix: | Human Plasma |
| Assay Range: | 0.8 - 400 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drug Assays |
Ibuprofen
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 40 µg/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | NSAID |
| Classification: | Drug Assays |
Ibuprofen
| Matrix: | Human Plasma |
| Assay Range: | 1 - 125 µg/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | NSAID |
| Classification: | Drug Assays |
Ibuprofen
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 200 ug/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | NSAID |
| Classification: | Drug Assays |
IFN-γ
| Matrix: | Human Serum |
| Assay Range: | 39.1 – 2500 pg/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | ECL (MSD) (9plex) |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
IFN-γ
| Matrix: | Human Serum |
| Assay Range: | 2.656 - 340 pg/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -70 |
| Platform: | Luminex (3Plex) |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
IL-10
| Matrix: | Human Serum |
| Assay Range: | 2.44 - 2,500 pg/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | ECL (MSD) (9plex) |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
IL-12p70
| Matrix: | Human Serum |
| Assay Range: | 9.77 – 2,500 pg/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | ECL (MSD) (9plex) |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
Links to Relevant Documents
Testimonials
Thanks for the good news, I’m happy to see that within less than a month you will have developed and validated the assay. Good Job!
QPS CLIENT