Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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Nifedipine
| Matrix: | Human Plasma |
| Assay Range: | 1 - 400 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Nimesulide
| Matrix: | Human Plasma |
| Assay Range: | 100 - 10,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | NSAID |
| Classification: | Drug Assays |
Nintedanib
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 50 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | LC-MS/MS |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Respiratory |
| Classification: | Drug Assays |
Nisoldipine
| Matrix: | Human Plasma |
| Assay Range: | 10 - 3,000 pg/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Nisoldipine
| Matrix: | Human Plasma |
| Assay Range: | 50 - 15,000 pg/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | |
| Therapy Area: | |
| Classification: | Drug Assays |
Nisoldipine
| Matrix: | Human Plasma |
| Assay Range: | 75 - 20,000 pg/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Nitrofurantoin
| Matrix: | Human Plasma |
| Assay Range: | 5 - 1,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drug Assays |
Norethindrone
| Matrix: | Human Plasma |
| Assay Range: | 0.05 to 10 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Women's Health |
| Classification: | Drug Assays |
Norgestimate Norgestrel
| Matrix: | Human Plasma |
| Assay Range: | 50 - 50,000 pg/mL 20 - 20,000 pg/mL |
| Sample Volume: | 0.5 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Women's Health |
| Classification: | Drug Assays |
Nortriptyline 10-OH-Nortriptyline
| Matrix: | Human Plasma |
| Assay Range: | 0.18 - 50 ng/mL 0.3 - 80 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antidepressant |
| Classification: | Drug Assays |
Olanzapine
| Matrix: | Human Plasma |
| Assay Range: | 0.500 - 100 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Dementia and Alzheimer's Disease |
| Classification: | Drug Assays |
Olmesartan
| Matrix: | Human Plasma |
| Assay Range: | 10- 3,000 ng/mL |
| Sample Volume: | 0.1mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drug Assays |
Olsalazine in presence of Mesalamine
| Matrix: | Human Plasma |
| Assay Range: | 8 - 2,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiinflammatory |
| Classification: | Drug Assays |
Omeprazole
| Matrix: | Human Plasma |
| Assay Range: | 20 - 2,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Gastrointestinal |
| Classification: | Drug Assays |
Omeprazole
| Matrix: | Human Plasma |
| Assay Range: | 5 - 5,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Gastrointestinal |
| Classification: | Drug Assays |
Ondansetron
| Matrix: | Human Plasma |
| Assay Range: | 0.5 - 500 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antiemetic |
| Classification: | Drug Assays |
Osimertinib
| Matrix: | Human Plasma |
| Assay Range: | 0.4 - 200 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drug Assays |
Ospemifene
| Matrix: | Human Serum |
| Assay Range: | 1 - 750 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Women's Health |
| Classification: | Drug Assays |
Ospemifene
4-OH-Ospemifene4′-OH-Ospemifene
4-OH-Ospemifene4′-OH-Ospemifene
| Matrix: | Human Serum |
| Assay Range: | 1 - 750 ng/mL 2 - 1,500 ng/mL2 - 1,500 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Women's Health |
| Classification: | Drug Assays |
Osteopontin
| Matrix: | Human Urine |
| Assay Range: | 0.313 - 20.0 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
Oxaliplatin
| Matrix: | Human Plasma |
| Assay Range: | 1.00 - 1,000 ngPt/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | ICP-MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drug Assays |
Oxaliplatin
| Matrix: | Human Plasma Ultrafiltrate |
| Assay Range: | 3.00 - 1,000 ngPt/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | ICP-MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drug Assays |
Oxaliplatin
| Matrix: | Human Plasma |
| Assay Range: | 1.00-1,000 ngPt/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | ICP-MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drug Assays |
Oxaliplatin
| Matrix: | Human Plasma Ultrafiltrate |
| Assay Range: | 3.00-1,000 ngPt/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | ICP-MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drug Assays |
Oxazepam
Lorazepam
Lorazepam
| Matrix: | Human Plasma |
| Assay Range: | 1 - 1,000 ng/mL 0.2 - 200 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | K2 EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Sedative |
| Classification: | Drug Assays |
Links to Relevant Documents
Testimonials
Thanks for the good news, I’m happy to see that within less than a month you will have developed and validated the assay. Good Job!
QPS CLIENT