Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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Copper (total)
| Matrix: | Human Urine |
| Assay Range: | 5.00-200 ng/mL |
| Sample Volume: | 50 µL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | ICP-MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Drug Assays |
Copper (total)
| Matrix: | Human Serum |
| Assay Range: | 50.0-5,000 ng/mL |
| Sample Volume: | 10 µL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | ICP-MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Drug Assays |
Corticosterone
| Matrix: | Mouse Plasma |
| Assay Range: | 1.0 - 145 ng/mL |
| Sample Volume: | 0.03 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
Corticosterone
| Matrix: | Rat Plasma |
| Assay Range: | 1.1 - 164 ng/mL |
| Sample Volume: | 0.03 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
Cortisol
| Matrix: | Dog Plasma |
| Assay Range: | 0.500 - 60.0 µg/dL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
Cortisol
| Matrix: | Human Plasma |
| Assay Range: | 0.500 - 60.0 µg/gL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | Citrate |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
Cortisol (free fraction)
| Matrix: | Human Serum |
| Assay Range: | 5.0 - 500 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
Cortisol (free freaction)
Prednisolone (free fraction)
Prednisolone (free fraction)
| Matrix: | Human Serum |
| Assay Range: | 5.00 - 500 ng/mL 1.00 - 500 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Antiinflammatory |
| Classification: | Drug Assays |
Cortisol
6ß-hydroxycortisol
6ß-hydroxycortisol
| Matrix: | Human Urine |
| Assay Range: | 1.00 - 1,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
Cortisol
6ß-hydroxycortisol
6ß-hydroxycortisol
| Matrix: | Human Urine |
| Assay Range: | 1 - 150 ng/mL 5 - 750 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
Cortisol
6ß-hydroxycortisol
6ß-hydroxycortisol
| Matrix: | Human Urine |
| Assay Range: | 1 - 150 ng/mL 5 - 750 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | UPLC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
Cortisol
Prednisolone
Prednisolone
| Matrix: | Human Serum |
| Assay Range: | 5.00 - 500 ng/mL 2.50 - 500 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Antiinflammatory |
| Classification: | Drug Assays |
Creatinine
| Matrix: | Human Urine |
| Assay Range: | 0.1 - 2 mM |
| Sample Volume: | 0.02 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | Colorimetric |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
Creatinine
| Matrix: | Human Urine |
| Assay Range: | 0.400 - 40.0 µg/mL |
| Sample Volume: | 0.01 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -20 |
| Platform: | HPLC-UV |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biochemical Biomarkers |
Cyclobenzaprine
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 60 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Muscle Relaxant |
| Classification: | Drug Assays |
Cyclobenzaprine
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 100 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Muscle Relaxant |
| Classification: | Drug Assays |
Cyclophosphamide
Fludarabine
Fludarabine
| Matrix: | Human Plasma |
| Assay Range: | 2.00 - 2,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC/MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drug Assays |
Cyclosporin A
| Matrix: | Human Whole Blood |
| Assay Range: | 5.00 - 5,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drug Assays |
Cyclosporin A
| Matrix: | Human Whole Blood |
| Assay Range: | 2 - 1,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC/MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drug Assays |
CYP2B6 (*5A, *9 , *18) Genotyping
| Matrix: | Human Whole Blood |
| Assay Range: | N.Ap. |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -80 |
| Platform: | TaqMan |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Genomic Biomarkers |
CYP2C19 (*2, *3, *4, *5, *6, *8) Genotyping
| Matrix: | Human Whole Blood |
| Assay Range: | N.Ap. |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -80 |
| Platform: | TaqMan |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Genomic Biomarkers |
CYP2C8 (*1B, *1C, *2, *3, *4) Genotyping
| Matrix: | Human Whole Blood |
| Assay Range: | N.Ap. |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -80 |
| Platform: | TaqMan; QuantStudio |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Genomic Biomarkers |
CYP2C9 (*2, *3, *4, *5) Genotyping
| Matrix: | Human Whole Blood |
| Assay Range: | N.Ap. |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -80 |
| Platform: | Pyrosequencing |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Genomic Biomarkers |
CYP2C9 (*8, *11, *13) Genotyping
| Matrix: | Human Whole Blood |
| Assay Range: | N.Ap. |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -80 |
| Platform: | TaqMan; 7900 |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Genomic Biomarkers |
CYP2D6 (*3, *3b, *5-2xN, *6, *7, *8, *10, *11, *14) Genotyping
| Matrix: | Human Whole Blood |
| Assay Range: | N.Ap. |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N.Ap. |
| Storage Temperature (°C): | -80 |
| Platform: | Pyrosequencing |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Genomic Biomarkers |
Links to Relevant Documents
Testimonials
Thanks for the good news, I’m happy to see that within less than a month you will have developed and validated the assay. Good Job!
QPS CLIENT