Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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					 Copper (total) 
									
				| Matrix: | Human Urine | 
| Assay Range: | 5.00-200 ng/mL | 
| Sample Volume: | 50 µL | 
| Anti-Coagulant: | N.Ap. | 
| Storage Temperature (°C): | -20 & -70 | 
| Platform: | ICP-MS | 
| Site: | QPS-NL | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Drug Assays | 
					 Copper (total) 
									
				| Matrix: | Human Serum | 
| Assay Range: | 50.0-5,000 ng/mL | 
| Sample Volume: | 10 µL | 
| Anti-Coagulant: | N.Ap. | 
| Storage Temperature (°C): | -20 & -70 | 
| Platform: | ICP-MS | 
| Site: | QPS-NL | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Drug Assays | 
					 Corticosterone 
									
				| Matrix: | Mouse Plasma | 
| Assay Range: | 1.0 - 145 ng/mL | 
| Sample Volume: | 0.03 mL | 
| Anti-Coagulant: | Heparin | 
| Storage Temperature (°C): | -20 | 
| Platform: | ELISA | 
| Site: | QPS-NL | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Biochemical Biomarkers | 
					 Corticosterone 
									
				| Matrix: | Rat Plasma | 
| Assay Range: | 1.1 - 164 ng/mL | 
| Sample Volume: | 0.03 mL | 
| Anti-Coagulant: | EDTA | 
| Storage Temperature (°C): | -20 | 
| Platform: | ELISA | 
| Site: | QPS-NL | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Biochemical Biomarkers | 
					 Cortisol 
									
				| Matrix: | Dog Plasma | 
| Assay Range: | 0.500 - 60.0 µg/dL | 
| Sample Volume: | 0.05 mL | 
| Anti-Coagulant: | EDTA | 
| Storage Temperature (°C): | -20 | 
| Platform: | ELISA | 
| Site: | QPS-NL | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Biochemical Biomarkers | 
					 Cortisol 
									
				| Matrix: | Human Plasma | 
| Assay Range: | 0.500 - 60.0 µg/gL | 
| Sample Volume: | 0.05 mL | 
| Anti-Coagulant: | Citrate | 
| Storage Temperature (°C): | -20 | 
| Platform: | ELISA | 
| Site: | QPS-NL | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Biochemical Biomarkers | 
					 Cortisol (free fraction) 
									
				| Matrix: | Human Serum | 
| Assay Range: | 5.0 - 500 ng/mL | 
| Sample Volume: | 0.2 mL | 
| Anti-Coagulant: | N.Ap. | 
| Storage Temperature (°C): | -20 | 
| Platform: | LC-MS/MS | 
| Site: | QPS-NL | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Biochemical Biomarkers | 
					 Cortisol (free freaction)
Prednisolone (free fraction) 
									
				Prednisolone (free fraction)
| Matrix: | Human Serum | 
| Assay Range: | 5.00 - 500 ng/mL 1.00 - 500 ng/mL | 
| Sample Volume: | 0.2 mL | 
| Anti-Coagulant: | N.Ap. | 
| Storage Temperature (°C): | -20 | 
| Platform: | LC/MS/MS | 
| Site: | QPS-NL | 
| CLIA: | No | 
| Therapy Area: | Antiinflammatory | 
| Classification: | Drug Assays | 
					 Cortisol
6ß-hydroxycortisol 
									
				6ß-hydroxycortisol
| Matrix: | Human Urine | 
| Assay Range: | 1.00 - 1,000 ng/mL | 
| Sample Volume: | 0.1 mL | 
| Anti-Coagulant: | N.Ap. | 
| Storage Temperature (°C): | -20 | 
| Platform: | LC/MS/MS | 
| Site: | QPS-NL | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Biochemical Biomarkers | 
					 Cortisol
6ß-hydroxycortisol 
									
				6ß-hydroxycortisol
| Matrix: | Human Urine | 
| Assay Range: | 1 - 150 ng/mL 5 - 750 ng/mL | 
| Sample Volume: | 0.2 mL | 
| Anti-Coagulant: | N.Ap. | 
| Storage Temperature (°C): | -20 | 
| Platform: | LC/MS/MS | 
| Site: | QPS-Delaware | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Biochemical Biomarkers | 
					 Cortisol
6ß-hydroxycortisol 
									
				6ß-hydroxycortisol
| Matrix: | Human Urine | 
| Assay Range: | 1 - 150 ng/mL 5 - 750 ng/mL | 
| Sample Volume: | 0.2 mL | 
| Anti-Coagulant: | N.Ap. | 
| Storage Temperature (°C): | -20 | 
| Platform: | UPLC/MS/MS | 
| Site: | QPS-Delaware | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Biochemical Biomarkers | 
					 Cortisol
Prednisolone 
									
				Prednisolone
| Matrix: | Human Serum | 
| Assay Range: | 5.00 - 500 ng/mL 2.50 - 500 ng/mL | 
| Sample Volume: | 0.05 mL | 
| Anti-Coagulant: | N.Ap. | 
| Storage Temperature (°C): | -20 | 
| Platform: | LC/MS/MS | 
| Site: | QPS-NL | 
| CLIA: | No | 
| Therapy Area: | Antiinflammatory | 
| Classification: | Drug Assays | 
					 Creatinine 
									
				| Matrix: | Human Urine | 
| Assay Range: | 0.1 - 2 mM | 
| Sample Volume: | 0.02 mL | 
| Anti-Coagulant: | N.Ap. | 
| Storage Temperature (°C): | -20 | 
| Platform: | Colorimetric | 
| Site: | QPS-Delaware | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Biochemical Biomarkers | 
					 Creatinine 
									
				| Matrix: | Human Urine | 
| Assay Range: | 0.400 - 40.0 µg/mL | 
| Sample Volume: | 0.01 mL | 
| Anti-Coagulant: | N.Ap. | 
| Storage Temperature (°C): | -20 | 
| Platform: | HPLC-UV | 
| Site: | QPS-NL | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Biochemical Biomarkers | 
					 Cyclobenzaprine 
									
				| Matrix: | Human Plasma | 
| Assay Range: | 0.2 - 60 ng/mL | 
| Sample Volume: | 0.2 mL | 
| Anti-Coagulant: | EDTA | 
| Storage Temperature (°C): | -20 & -70 | 
| Platform: | LC/MS/MS | 
| Site: | QPS-India | 
| CLIA: | No | 
| Therapy Area: | Muscle Relaxant | 
| Classification: | Drug Assays | 
					 Cyclobenzaprine 
									
				| Matrix: | Human Plasma | 
| Assay Range: | 0.1 - 100 ng/mL | 
| Sample Volume: | 0.1 mL | 
| Anti-Coagulant: | EDTA | 
| Storage Temperature (°C): | -20 & -70 | 
| Platform: | LC/MS/MS | 
| Site: | QPS-Delaware | 
| CLIA: | No | 
| Therapy Area: | Muscle Relaxant | 
| Classification: | Drug Assays | 
					 Cyclophosphamide
Fludarabine 
									
				Fludarabine
| Matrix: | Human Plasma | 
| Assay Range: | 2.00 - 2,000 ng/mL | 
| Sample Volume: | 0.1 mL | 
| Anti-Coagulant: | EDTA | 
| Storage Temperature (°C): | -20 | 
| Platform: | LC/MS/MS | 
| Site: | QPS-NL | 
| CLIA: | No | 
| Therapy Area: | Oncology | 
| Classification: | Drug Assays | 
					 Cyclosporin A 
									
				| Matrix: | Human Whole Blood | 
| Assay Range: | 5.00 - 5,000 ng/mL | 
| Sample Volume: | 0.1 mL | 
| Anti-Coagulant: | EDTA | 
| Storage Temperature (°C): | -20 & -70 | 
| Platform: | LC/MS/MS | 
| Site: | QPS-NL | 
| CLIA: | No | 
| Therapy Area: | Antibiotic | 
| Classification: | Drug Assays | 
					 Cyclosporin A 
									
				| Matrix: | Human Whole Blood | 
| Assay Range: | 2 - 1,000 ng/mL | 
| Sample Volume: | 0.1 mL | 
| Anti-Coagulant: | Heparin | 
| Storage Temperature (°C): | -20 & -70 | 
| Platform: | LC/MS/MS | 
| Site: | QPS-Delaware | 
| CLIA: | No | 
| Therapy Area: | Antibiotic | 
| Classification: | Drug Assays | 
					 CYP2B6 (*5A, *9 , *18) Genotyping 
									
				| Matrix: | Human Whole Blood | 
| Assay Range: | N.Ap. | 
| Sample Volume: | 0.2 mL | 
| Anti-Coagulant: | N.Ap. | 
| Storage Temperature (°C): | -80 | 
| Platform: | TaqMan | 
| Site: | QPS-Delaware | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Genomic Biomarkers | 
					 CYP2C19 (*2, *3, *4, *5, *6, *8) Genotyping 
									
				| Matrix: | Human Whole Blood | 
| Assay Range: | N.Ap. | 
| Sample Volume: | 0.2 mL | 
| Anti-Coagulant: | N.Ap. | 
| Storage Temperature (°C): | -80 | 
| Platform: | TaqMan | 
| Site: | QPS-Delaware | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Genomic Biomarkers | 
					 CYP2C8 (*1B, *1C, *2, *3, *4) Genotyping 
									
				| Matrix: | Human Whole Blood | 
| Assay Range: | N.Ap. | 
| Sample Volume: | 0.2 mL | 
| Anti-Coagulant: | N.Ap. | 
| Storage Temperature (°C): | -80 | 
| Platform: | TaqMan; QuantStudio | 
| Site: | QPS-Delaware | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Genomic Biomarkers | 
					 CYP2C9 (*2, *3, *4, *5) Genotyping 
									
				| Matrix: | Human Whole Blood | 
| Assay Range: | N.Ap. | 
| Sample Volume: | 0.2 mL | 
| Anti-Coagulant: | N.Ap. | 
| Storage Temperature (°C): | -80 | 
| Platform: | Pyrosequencing | 
| Site: | QPS-Delaware | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Genomic Biomarkers | 
					 CYP2C9 (*8, *11, *13) Genotyping 
									
				| Matrix: | Human Whole Blood | 
| Assay Range: | N.Ap. | 
| Sample Volume: | 0.2 mL | 
| Anti-Coagulant: | N.Ap. | 
| Storage Temperature (°C): | -80 | 
| Platform: | TaqMan; 7900 | 
| Site: | QPS-Delaware | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Genomic Biomarkers | 
					 CYP2D6 (*3, *3b, *5-2xN, *6, *7, *8, *10, *11, *14) Genotyping 
									
				| Matrix: | Human Whole Blood | 
| Assay Range: | N.Ap. | 
| Sample Volume: | 0.2 mL | 
| Anti-Coagulant: | N.Ap. | 
| Storage Temperature (°C): | -80 | 
| Platform: | Pyrosequencing | 
| Site: | QPS-Delaware | 
| CLIA: | No | 
| Therapy Area: | N/A | 
| Classification: | Genomic Biomarkers | 
Links to Relevant Documents
Testimonials
						Thanks for the good news, I’m happy to see that within less than a month you will have developed and validated the assay. Good Job!					
									
								QPS CLIENT			
		 
				 
						 
						 
															 
								 
								 
								