Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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Cimetidine
| Matrix: | Human Plasma |
| Assay Range: | 50 - 5,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antacid |
| Classification: | Drugs |
Cimetidine
| Matrix: | Human Plasma |
| Assay Range: | 15 - 8,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antacid |
| Classification: | Drugs |
CK18 capsase-cleaved (M30)
| Matrix: | Human Serum |
| Assay Range: | 50 - 1,000 U/L |
| Sample Volume: | 0.025 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biomarkers |
CK18 total (M65)
| Matrix: | Human Serum |
| Assay Range: | 25 - 2,000 U/L |
| Sample Volume: | 0.025 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biomarkers |
Clarithromycin
| Matrix: | Human Plasma |
| Assay Range: | 25 - 10,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drugs |
Clopidogrel
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 10 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Taiwan |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Cocaine
Benzoylecgonine
| Matrix: | Human Plasma |
| Assay Range: | 5 - 500 ng/mL 10 - 1,000 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Stimulant |
| Classification: | Drugs |
Colchicine
| Matrix: | Human Plasma |
| Assay Range: | 40 - 8,000 pg/mL |
| Sample Volume: | 0.3 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Gout |
| Classification: | Drugs |
Complement 3a (C3a)
| Matrix: | Human Plasma |
| Assay Range: | 10.0 - 974 ng/mL |
| Sample Volume: | 10 µL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Biomarkers |
Complement 4 (C4)
| Matrix: | Human Plasma |
| Assay Range: | 14.5 - 1,856 µg/mL |
| Sample Volume: | 0.08 mL |
| Anti-Coagulant: | Citrate |
| Storage Temperature (°C): | -70 |
| Platform: | Nephelometry |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Immunology |
| Classification: | Biomarkers |
Complement 5a (C5a)
| Matrix: | Human Plasma |
| Assay Range: | 2.08 - 19.7 ng/mL |
| Sample Volume: | 20 µL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Immunology |
| Classification: | Biomarkers |
Complement Total (CH50)
| Matrix: | Human Serum |
| Assay Range: | 34 - 304 U eq/mL |
| Sample Volume: | 30 µL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biomarkers |
Copper
| Matrix: | Human Urine |
| Assay Range: | 50.0 - 800 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 & -80 |
| Platform: | ICP-MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biomarkers |
Copper (total)
| Matrix: | Human Serum |
| Assay Range: | 50.0 - 5,000 ng/mL |
| Sample Volume: | 10 µL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | ICP-MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Drugs |
Copper (total)
| Matrix: | Human Urine |
| Assay Range: | 5.00 - 200 ng/mL |
| Sample Volume: | 50 µL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | ICP-MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Drugs |
Corticosterone
| Matrix: | Mouse Plasma |
| Assay Range: | 1.0 - 145 ng/mL |
| Sample Volume: | 0.03 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biomarkers |
Corticosterone
| Matrix: | Rat Plasma |
| Assay Range: | 1.1 - 164 ng/mL |
| Sample Volume: | 0.03 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biomarkers |
Cortisol
6β-Hydroxycortisol
| Matrix: | Human Urine |
| Assay Range: | 1 - 150 ng/mL 5 - 750 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biomarkers |
Cortisol
6β-Hydroxycortisol
| Matrix: | Human Urine |
| Assay Range: | 1 - 150 ng/mL 5 - 750 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biomarkers |
Cortisol
| Matrix: | Dog Plasma |
| Assay Range: | 0.500 - 60.0 µg/dL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biomarkers |
Cortisol
| Matrix: | Human Plasma |
| Assay Range: | 0.500 - 60.0 µg/gL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | Citrate |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biomarkers |
Cortisol (free fraction)
| Matrix: | Human Serum |
| Assay Range: | 5.0 - 500 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Biomarkers |
Cortisol (free freaction)
Prednisolone (free fraction)
| Matrix: | Human Serum |
| Assay Range: | 5.00 - 500 ng/mL 1.00 - 500 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Anti-inflammatory |
| Classification: | Drugs |
Creatinine
| Matrix: | Human Urine |
| Assay Range: | 0.1 - 2 mM |
| Sample Volume: | 0.02 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | Colorimetric |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Vascular, Cardiovascular |
| Classification: | Biomarkers |
Cyclobenzaprine
| Matrix: | Human Plasma |
| Assay Range: | 0.2 - 60 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Muscle Relaxant |
| Classification: | Drugs |
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