Validated QPS Assays
The vast majority of today’s modern bioanalytical methods for pharmacokinetics, pharmacodynamics, and immunogenicity assessment are based on mass spectrometry and/or immuno-bioanalytical approaches. However, for a small but important number of compounds, LC MS/MS or LBA are less than satisfactory. A good alternative is Inductively Coupled Plasma Mass Spectrometry (ICP-MS). In ICP MS, the samples are ionized by an inductively coupled plasma (ionization source) and the ions of interest are separated, detected, and quantitated by a mass spectrometer.
The QPS Assay Finder contains a broad range of validated assays for all of your bioanalytical needs.
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Cyclobenzaprine
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 100 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Muscle Relaxant |
| Classification: | Drugs |
Cyclophosphamide
Fludarabine
| Matrix: | Human Plasma |
| Assay Range: | 2.00 - 2,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 |
| Platform: | LC-MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Oncology |
| Classification: | Drugs |
Cyclosporin A
| Matrix: | Human Whole Blood |
| Assay Range: | 5.00 - 5,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drugs |
Cyclosporin A
| Matrix: | Human Whole Blood |
| Assay Range: | 2 - 1,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Antibiotic |
| Classification: | Drugs |
CYP2B6 (*5A, *9 , *18) Genotyping
| Matrix: | Human Whole Blood |
| Assay Range: | N/A |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -80 |
| Platform: | TaqMan; 7900 |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Genomic |
CYP2C19 (*2, *3, *4, *5, *6, *8)
Genotyping
| Matrix: | Human Whole Blood |
| Assay Range: | N/A |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -80 |
| Platform: | TaqMan; 7900 |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Genomic |
CYP2C8 (*1B, *1C, *2, *3, *4) Genotyping
| Matrix: | Human Whole Blood |
| Assay Range: | N/A |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -80 |
| Platform: | TaqMan; QuantStudio |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Genomic |
CYP2C9 (*8, *11, *13) Genotyping
| Matrix: | Human Whole Blood |
| Assay Range: | N/A |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -80 |
| Platform: | TaqMan; 7900 |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Genomic |
CYP2D6 (*4, *9, *15, *17, *18, *19, *20, *29, *35, *38, *40, *41)
Genotyping; Copy Number Variation (*5/*2xN)
| Matrix: | Human Whole Blood |
| Assay Range: | N/A |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -80 |
| Platform: | TaqMan; 7900 |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | N/A |
| Classification: | Genomic |
Cystatin C
| Matrix: | Human Serum |
| Assay Range: | 3.12 - 50 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Nephrology |
| Classification: | Biomarkers |
Cystatin C
| Matrix: | Human Urine |
| Assay Range: | 3.12 - 50 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Nephrology |
| Classification: | Biomarkers |
Cystatin C
| Matrix: | Human Serum |
| Assay Range: | 0.156 - 3,000 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Nephrology |
| Classification: | Biomarkers |
Cystatin C
| Matrix: | Human Urine |
| Assay Range: | 1.56 - 400 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -70 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Nephrology |
| Classification: | Biomarkers |
Cystatin C
| Matrix: | Human Plasma |
| Assay Range: | 2 - 100 ng/mL |
| Sample Volume: | 0.01 mL |
| Anti-Coagulant: | Heparin |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Nephrology |
| Classification: | Biomarkers |
Cystatin C
| Matrix: | Human Urine |
| Assay Range: | 3.13 - 100 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Nephrology |
| Classification: | Biomarkers |
Cystatin C
| Matrix: | Human Serum |
| Assay Range: | 3.13 - 100 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | N/A |
| Storage Temperature (°C): | -20 |
| Platform: | ELISA |
| Site: | QPS-NL |
| CLIA: | No |
| Therapy Area: | Nephrology |
| Classification: | Biomarkers |
Cytokine Panel: MSD ProInflammatory 10-Plex
| Matrix: | Human Plasma |
| Assay Range: | varies per cytokine |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | ECL (MSD) (10plex) |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Nephrology |
| Classification: | Biomarkers |
Cytokine Panel: MSD ProInflammatory 10-Plex
| Matrix: | Human CSF |
| Assay Range: | varies per cytokine |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -70 |
| Platform: | ECL (MSD) (10plex) |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Inflammation |
| Classification: | Biomarkers |
d-Amphetamine
l-Amphetamine
| Matrix: | Human Plasma |
| Assay Range: | 0.1 - 100 ng/mL 0.1 - 100 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Stimulant |
| Classification: | Drugs |
Dabigatran (Free)
| Matrix: | Human Plasma |
| Assay Range: | 1 - 400 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Dabigatran (Total)
| Matrix: | Human Plasma |
| Assay Range: | 1 - 500 ng/mL |
| Sample Volume: | 0.05 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Daclatasvir
| Matrix: | Human Plasma |
| Assay Range: | 10 - 3,000 ng/mL |
| Sample Volume: | 0.1 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antiviral - HCV |
| Classification: | Drugs |
Dalteparin Sodium (anti-Factor IIa)
| Matrix: | Human Plasma |
| Assay Range: | 1.0 - 8.0 µg/mL |
| Sample Volume: | 0.025 mL |
| Anti-Coagulant: | Citrate |
| Storage Temperature (°C): | -70 |
| Platform: | Activity / Colorimetric |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Dalteparin Sodium (anti-Factor Xa)
| Matrix: | Human Plasma |
| Assay Range: | 1.0 - 10.0 µg/mL |
| Sample Volume: | 0.025 mL |
| Anti-Coagulant: | Citrate |
| Storage Temperature (°C): | -70 |
| Platform: | Activity / Colorimetric |
| Site: | QPS-Delaware |
| CLIA: | No |
| Therapy Area: | Cardiovascular |
| Classification: | Drugs |
Dapagliflozin in presence of Metformin, Empagliflozin, Linagliptin, Saxagliptin, 5-hydroxy Saxagliptin, Valsartan & Sacubitril
| Matrix: | Human Plasma |
| Assay Range: | 1 - 400 ng/mL |
| Sample Volume: | 0.2 mL |
| Anti-Coagulant: | EDTA |
| Storage Temperature (°C): | -20 & -70 |
| Platform: | LC-MS/MS |
| Site: | QPS-India |
| CLIA: | No |
| Therapy Area: | Antidiabetic |
| Classification: | Drugs |
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