Infographics In human cells infected by the human immunodeficiency virus (HIV), virus particles can leave behind part of their genetic material, which gets incorporated into the cellular DNA. Known as provirus, this genetic material can persist indefinitely in infected human cells and can lead to resurgence of the disease. Using cutting-edge gene-sequencing technology to analyze …
Superbugs Emerging as Super-Big Problem, Demand Urgent Attention
Infographics Results of a comprehensive global study of antimicrobial resistance (AMR) show that infections caused by antibiotic-resistant bacteria — also known as “superbugs” — were among the leading causes of death in 2019, killing more people than HIV/AIDS or malaria. The report, published in the Lancet in January, estimates that 4.95 million people died from …
New Migraine Drugs Could Have Life-Changing Effects
The U.S. Centers for Disease Control and Prevention (CDC) report that migraines, or severe headaches, affect more than 15 percent of U.S. adults. That adds up to more than 39 million Americans afflicted with migraine attacks lasting up to 72 hours. These debilitating episodes cause severe pain in the head, face, and neck, often sending …
Deadly Candida Auris Found in Nature for the First Time
Since its first reported occurrence in 2009, the fungus Candida auris quickly spread worldwide. Now it is found in more than 34 countries and is considered a global public health threat, causing serious and sometimes fatal infections. This microorganism is highly resistant to antifungal medicines, requires specialized lab equipment for identification, and is easily transmitted …
At Long Last, an Effective Malaria Vaccine
Malaria has long been one of the most threatening diseases in the tropical world. About 229 million cases were recorded in 2019, and 409,000 deaths, according to the World Health Organization (WHO). Of those deaths, 67 percent occurred in children under age five. 94 percent of all cases and deaths occur in Africa. The WHO …
A Gene Therapy Startup Engages in Horseplay to Test New Osteoarthritis Therapy
Osteoarthritis is a debilitating and painful wearing down of joint cartilage tissues. Every year, more than three million people in the U.S. (and millions more worldwide) are diagnosed with the disease. Current therapies consist mainly of either steroids or non-steroidal anti-inflammatory drugs (NSAIDs), both of which are largely ineffective, especially as the disease progresses. Biologics …
The Need Grows for New Antifungal Therapies
Unless you’re working in a highly controlled environment like a cleanroom, it’s safe to assume you are surrounded by fungi. Millions of fungal species live in soil, grow on plants, not to mention on our bodies. Every inhalation can introduce fungal spores. If you have never had to worry about this, it is because you …
Human Immune System Beats HIV for the First Time
The Centers for Disease Control and Prevention (CDC) describes human immunodeficiency virus (HIV) as a virus that attacks the body’s immune system. Without treatment, HIV can cause acquired immunodeficiency syndrome (AIDS). While there is currently no effective cure for HIV, scientists recently made a groundbreaking discovery: some rare patients, known as “elite controllers,” may be able to …
Interested in Plaque-Associated Inflammation?
Are you interested in exploring plaque-associated inflammation? QPS Neuropharmacology, a division of QPS (a leading CRO for drug development), is your partner for the visualization and quantification of plaque-associated inflammation. With our on-site, highly predictive disease models and extensive experience with clinical studies, QPS Neuropharmacology is an excellent choice for biopharmaceutical companies of all sizes focusing …
QPS has a Strong Competency in Alzheimer Research
The results of a research collaboration between the neuroscience group of QPS Netherlands B.V. and Professor Peter Paul de Deyn and coworkers of the Department of Neurology and Alzheimer Research Center, University Medical Center Groningen, were recently published in the European Journal of Clinical Investigations (Naudé et al. 2017) entitled “Dynamics of neutrophil gelatinase-associated lipocalin …